It was hypothesized that when relative dietary intake of tryptophan per capita is low compared to certain other amino acids, less serotonin is formed in brain neurons, and suicide rates tend to be high. The hypothesis was supported for males and for both sexes combined.
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References
1.
DurkheimE., Suicide, Free Press, New York, 1966.
2.
DublinL. I., Suicide: A Sociological and Statistical Study, Ronald Press, New York, 1963.
3.
DouglasJ. D., The Social Meaning of Suicide, Princeton University Press, Princeton, 1967.
4.
RuzickaL. T., Suicide: 1950 to 1971, World Health Statistics Report, 29, pp. 306–413, 1976.
5.
NarollR., The Moral Order, Sage Publications, Beverly Hills, 1983.
6.
ÅsbergM.TraskmanL., Studies of CSF 5-HIAA in Depression and Suicidal Behavior, in Serontonin: Current Aspects of Neurochemistry and Function, HaberB. (eds.), Plenum Press, New York, pp. 739–752, 1981.
7.
ÅsbergM.TraskmanL.ThorenP., 5-HIAA in the Cerebrospinal Fluid—A Biochemical Suicide Predictor?Archives of General Psychiatry, 33, p. 1193, 1976.
8.
LapinI. P.OxenkrugG. F., Intensification of the Central Serotoninergic Precesses as a Possible Determinant of the Thymoleptic Effect, Lancet, 1, pp. 132–136, 1969.
9.
CoppenA.ShawD. M.FarrellM. B., Potentiation of the Antidepressive Effect of a Monoamineoxidase Inhibitor by Tryptophan, Lancet, 1, pp. 79–81, 1963.
10.
MφllerS. E.KirkL.FremmingK. H., Plasma Amino Acids as an Index for Subgroups in Manic Depressive Psychosis: Correlation to Effect of Tryptophan, Psychopharmacology, 49, pp. 205–213, 1976.
11.
WallinderJ., et al., Potentiation of the Antidepressant Action of Clomipramine by Tryptophan, Archives of General Psychiatry, 33, pp. 1384–1389, 1976.
12.
MillardS. S.GalE. M., The Contribution of 5-hydroxyindolepyruvic Acid to Cerebral 5-hydroxyindole Metabolism, International Journal of Neuroscience, 1, pp. 211–218, 1971.
13.
FernstromJ. D.FallerD. V., Neutral Amino Acids in the Brain: Changes in Response to Food Ingestion, Journal of Neurochemistry, 30, pp. 1531–1538, 1978.
14.
FernstromJ. D., Dietary Precursors and Brain Neurotransmitter Formation, Annual Review of Medicine, 32, pp. 413–425, 1981.
15.
FAO, Amino-Acid Content of Foods and Biological Data of Proteins, FAO, Rome, 1970.
16.
FAO, Food Balance Sheets 1975–1977 Average and Per Capita Food Supplies 1961–1965 Average 1967 to 1977, FAO, Rome, 1980.
17.
World Health Statistics Annual, Vol. 1: Vital Statistics and Causes of Death, World Health Statistics, Geneva, 1977–1981.