This study assesses behavioral disorders and depression in 50 patients with chronic viral hepatitis (32 patients with HBV and 18 patients with HCV). A psychodiagnostic protocol composed of the IBQ and the BDI was administered to the entire sample in two stages—at the time of recruitment (T1) and after 8 months, when patients were receiving pharmacological treatment (T2). The results showed a predominance of behavioral disorders and depression in patients with HCV compared to HBV patients, although all patients with chronic viral hepatitis, despite reduction in viral load, displayed reduced quality of working life and relationships.
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References
1.
American Psychiatric Association (APA). (2000). DSM-IV Manuale diagnostico e statistico dei disturbi mentali Milano. Masson, Italy: Elsevier.
2.
BaranyiA.MeinitzerA.StepanA.MatejkaJ.StauberR.KapfhammerH. P. (2011, October). Interferon α bei Patienten mit chronischer Hepatitis C Biopsychosoziale Auswirkungen. Nervenarzt, 29, 1–7.
3.
BeckA. T.WardC. H.MendelsonM.MockI. & ErbaughI. (1961). An inventory for measuring depression. Archives of General Psychiatry, 4, 561.
4.
BeloborodovaE. I.LambrovaE. G.BeloborodovaE. V.OstankoV. L.AlekseevaA. S.KalachevaT. P. (2010a). Somatopsychic manifestations in patients with chronic viral hepatitis. Klin Med (Mosk), 88(5), 42–45.
5.
BeloborodovaE. I.LambrovaE. G.BeloborodovaE. V.OstankoV. L.AlekseevaA. S.KalachevaT. P. (2010b). Quality of life indices in patients with chronic viral hepatitis. Ter Arkh, 82(11), 41–45.
6.
CruznevesA.DickensC. & XavierM. (2006). Comorbilidade entre hepatite C e depressão Aspectos Epidemiológicos e Etiopatogénicos. Acta Med Port, 19, 21–28.
7.
FosterG. B. (2009). Quality of life considerations for patients with chronic hepatitis C. Journal of Viral Hepatitis, 16(9), 605–611.
8.
GrassiL.SatrianoJ.SerraA.BiancosinoB.ZotosG.SighinolfiL. (2002, November-December). Emotional stress, psychosocial variables and coping associated with hepatitis C virus and human immunodeficiency virus infections in intravenous drug users. Psychotherapy and Psychosomatics, 71(6), 342–349.
9.
HilsabeckR. C.HassaneinT. I.CarlsonM. D.ZieblerE. A. & PerryW. (2003). Cognitive functioning and psychiatric symptomatology in patients with chronic hepatitis C. Journal of the International Neuropsychological Society, 9, 847–854.
10.
HoareM.GelsonW. T. H.DasA.FletcherJ. M.DaviesS. E.CurranM. D. (2010, August). CD4+ T-lymphocyte telomere length is related to fibrosis stage, clinical outcome and treatment response in chronic hepatitis C virus infection. Journal of Hepatology, 53(2), 252–260.
11.
KallmanJ.O'NeilM. M.LariveB.BoparaiN.CalabreseL. & YounossiZ. M. (2007, October). Fatigue and health-related quality of life (HRQL) in chronic hepatitis C virus infection. Digestive Disease Science, 52(10), 2531–2539.
12.
KaraivazoglouK.AssimakopoulosK.ThomopoulosK.TheocharisG.MessinisL.SakellaropoulosGeorge G. (2007, August). Neuropsychological function in Greek patients with chronic hepatitis C. Liver International, 27(6), 798–805.
13.
KaraivazoglouK.IconomouG.TriantosC.HyphantiT.ThomopoulosK.LagadinouM. (2010, October-December). Fatigue and depressive symptoms associated with chronic viral hepatitis patients. Health-related quality of life (HRQOL). Annals of Hepatology, 9(4), 419–427.
14.
OrruM. G.BaitaA.ChessaL.FarciM. G.CarpinielloB. & ParranteC. M. (2005). Hepatitis and psichiatric symptoms. Giorn Ital Psicopat, 11, 179–183.
15.
PantigaC.RodrigoL. R.CuestM.LopezL. & AriasJ. L. (2003). Cognitive deficits in patients with hepatic cirrhosis and in liver transplant recipients. Journal of Neuropsychiatry and Clinical Neuroscience, 15, 84–89.
16.
PerryW.HilsabeckR. C. & HassaneinT. I. (2008, February). Cognitive dysfunction in chronic hepatitis C: A review. Digestive Disease Science, 53(2), 307–321.
17.
PilowskyI. & NeilSpence D. (1982). Illness Behaviour Questionnaire (IBQ) (Adatt. Ital. a cura di G.Fava e M Bernardi). Organizzazioni Speciali—Firenze.
18.
SenturkH.TahanV.CanbakanB.UrazS.UlgerY.OzarasR. (2008, May). Chronic hepatitis C responds poorly to combination therapy in chronic hepatitis B carriers. Netherlands Journal of Medicine, 66(5), 191–195.
19.
SinghN.GayowskiT.WagenerM. M. & MarinoI. R. (1997, October), Vulnerability to psychologic distress and depression in patients with end-stage liver disease due to hepatitis C virus. Clinical Transplant, 11(5 Pt 1), 406–411.
20.
TillmannH. L.WieseM.BraunY.WiegandJ.TenckhoffS.MossnerJ. (2011). Quality of life in patients with various liver diseases. Journal of Viral Hepatitis, 18, 252–261.
21.
WeinsteinA. A.Kallman-PriceJ.StepanovaM.PomsL. W.FangY.MoonJ. (2011, March-April). Depression in patients with nonalcoholic fatty liver disease and chronic viral hepatitis B and C. Psychosomatics, 52(2), 127–132.
