This article reviews the psychiatric complications of malaria. A case of malaria infection is described. The diagnoses, treatment, and neuropsychiatric complications of acute and chronic malaria infection are discussed. The treatment of malaria and its complications are summarized.
DugbarteyATDougearteyMTApedoMY. Delayed neuropsychiatric effects of malaria in Ghana. Journal of Nervous and Mental Disorders1998; 186: 183–186.
2.
RomanGC. Cerebral malaria: The unsolved riddle. Journal of Neurological Science1991; 101: 1–6.
3.
VarneyNRRobertsRJSpringerJAConnellSKWoodPS. Neuropsychiatric sequelae of cerebral malaria in Vietnam veterans. Journal of Nervous and Mental Disorders1997; 185: 695–703.
4.
OsuntokunBO. The nervous system in malaria. African Journal of Medical Science1983; 12: 165–172.
5.
GorbachSLBartlettJFBlacklowNR. Infectious diseases. 2nd Edition. Philadelphia: W. B. Saunders, 1998.
6.
SenanayakeNde SilvaHJ. Delayed cerebellar ataxia complicating falciparum malaria: A clinical study of 74 patients. Journal of Neurology1994; 241: 456–459.
7.
MaiNTHDayMPJChuongLVWalkerDPhuNHBethellDBHienTTWhiteMJ. Post malaria neurological syndrome. Lancet1996; 348: 917–921.
8.
DugbarteyATSpellacyFJ. Simple reaction time and cognitive information processing efficiency after cerebral malaria in Ghanaian children. Neurology and Infectious Epidemiology1997; 2: 141–144.
9.
MuntendamAHJaffarSBleichrodtNVan HensbroekMB. Absence of neuropsychological sequelae following cerebral malaria in Gambian children. Transactions of the Royal Society of Tropical Medicine Hygiene1996; 90: 391–394.
10.
KwiatkowskiDCannonJGManogueKR. Tumor necrosis factor induction in falciparum malaria and its association with schizont rupture. Experiential Immunology1989; 77: 361–366.
11.
GernaatHB. Malaria presenting as atypical depression. British Journal of Psychiatry1990; 157: 594–595.
12.
PrakashMVSteinG. Malaria presenting as atypical depression. British Journal of Psychiatry1990; 157: 783.
13.
LovestoneS. Chloroquine-induced mania. British Journal of Psychiatry1991; 159: 164–165.
14.
ClattenburgRNDonnellyCL. Case study: Neuropsychiatric symptoms associated with the antimalarial agentmefloquine. Journal of the American Academy of Child and Adolescent Psychiatry1997; 36: 1606–1608.
15.
SilverstonePH. Prevalence of psychiatric disorders in medical inpatients. Journal of Nervous and Mental Disorders1996; 184: 43–51.
16.
CrowTJ. Is schizophrenia an infectious disease?Lancet1983; 173–175.
17.
DaroffRBDellerJJKasrlAJ. Cerebral malaria. Journal of the American Medical Association1967; 202: 679–682.
18.
RichardsonEDRobertsRJHinesMEVarneyNR. Long term sequelae of malaria in Vietnam veterans. VA Practitioner1989; 2: 51–60.
19.
BygbjegLCLanngCE. Coli septicaemia in cerebral malaria. Transactions of the Royal Society of Tropical Medicine Hygiene1982; 76: 705.
