This is the second part of a two-part series reviewing the published literature of smokeless tobacco in the United States. The article explores smokeless tobacco as a pharmacologically addicting substance, educational interventions designed to prevent use or help users quit, and outlines areas of future research.
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References
1.
OrfilaB., Memoire sur la nicotine et sur la conicine, Ann Hygiene Pub, 45, pp. 147–230, 1851.
2.
WerleE.MeyerA., Uber den Abbau von Tabakalkaloiden surch tierische Gewebe, Biochemische Zeitschrift, 321:(B), pp. 221–235, 1950.
3.
LarsonP. S.HaagH. B.SilvetteH., Tobacco. Experimental and Clinical Studies. A Comprehensive Account of the World Literature, Williams and Wilkens Co., Baltimore, 1961.
4.
LarsonP. S.SilvetteH., Tobacco. Experimental and Clinical Studies. A Comprehensive Account of the World Literature. Supplement I, Williams and Wilkens Co., Baltimore, 1968.
5.
LarsonP. S.SilvetteH., Tobacco. Experimental and Clinical Studies. A Comprehensive Account of the World Literature. Supplement H, Williams and Wilkens Co., Baltimore, 1971.
6.
RussellM. A. H.FeyerabendC., Cigarette Smoking: A Dependence Disorder, Br. J. Med. Psych., 8:(1), pp. 29–57.
7.
Armstrong-JonesS., Tobacco, Its Use and Abuse: From the Nervous and Mental Aspect, Practioner, pp. 6–19, 1929.
8.
JohnstonL. M., Tobacco Smoking and Nicotine, Lancer, 243, p. 743, 1942.
9.
National Institute on Drug Abuse, NIH/DHHS: Drug Abuse and Drug Abuse Research, the First in a Series of Triennial Reports to Congress from the Secretary, Department of Health and Human Services, U.S. Government Printing Office, Washington, D.C., 1984.
10.
U.S. Department of Health and Human Services, Nicotine. Drug Abuse and Drug Abuse Research, The Second Triennial Report to Congress from the Secretary, Department of Health and Human Services (DHHS Publ. No. (ADM) 87-1486. U.S. Government Printing Office, Washington, D.C., pp. 93–119, 1987.
11.
U.S. Department of Health and Human Service: Why people smoke cigarettes, USPHS No. PHS-83-50195, U.S. Government Printing Office, Washington, D.C., 1983.
12.
U.S. Public Health Service, The Health Consequences of Using Smokeless Tobacco, A Report of the Advisory Committee to the Surgeon General. DHEW Publication No. (PHS) 86-2874. U.S. Government Printing Office, Washington, D.C., 1986.
13.
SchusterC. R., Addiction: Report of the Task Force on Smoking, World Smoking and Health, 5, p. 22, 1980.
14.
JaffeJ. H., Drug Addiction and Drug Abuse, In Goodman and Gillman's Pharmacological Basis of Therapeutics, GillmanA. G.GoodmanL. S.RallT. W.MuradF. (eds.), Macmillan, New York, pp. 532–581, 1985.
15.
World Health Organization, WHO Expert Committee on Drug Dependence, Twenty-third Report, Technical Series 741, Geneva, 1987.
16.
JasinskiD. R., Assessment of the Abuse Potential of Morphine-like Drugs (Methods Used in Man), In Handbook of Experimental Psychology, MartinW. R. (ed.), Springer-Verlag, Heidelberg, pp. 197–253, 1977.
17.
JasinskiD. R.JohnsonR. E.HenningfieldJ. E., Abuse Liability Assessment in Human Subjects, Trends Pharmacol. Sci., 5, pp. 196–200, 1984.
18.
BradyJ. V.LukasS. E., Testing Drugs for Physical Dependence Potential and Abuse Liability, National Institutes on Drug Abuse Research Monograph, 52, (DHHS Pub. No. (ADM) 84-1332, U.S. Government Printing Office, Washington, D.C.
19.
ThompsonT.UnnaK. R., Predicting Dependence Liability of Stimulant and Depressant Drugs, University Park Press, Baltimore, 1977.
20.
AustinG. A., Perspectives on the History of Psychoactive Substance Use, National Institute on Drug Abuse, Research Issues, 24. (DHEW Publ. No. (ADM) 79-810), U.S. Government Printing Office, Washington, D.C., 1979.
21.
GloverE. D., Conducting Smokeless Tobacco Cessation Clinics, Am. J. Public Health, 76, p. 207, 1986.
22.
GritzE. R.Baer-WeissV.BenowitzN. L.Van VunakisH.JarvikM. E., Plasma Nicotine and Cotinine Concentrations in Habitual Smokeless Tobacco Users, Clin. Pharmacol. Ther.30, pp. 201–209, 1981.
23.
RosenbergJ.BenowitzN.PeytonJ.WilsonK. M., Disposition Kinetics and Effects of Intravenous Nicotine, Clin. Pharmacol. Ther, 28, pp. 517–522, 1980.
24.
PinborgJ. J.AxelsenN. H., New Age for Non-smoked Tobacco, Lancet, 1, p. 775, 1980.
25.
BenowitzN. L.HallS. M.HerningR. I.JacobsP.JonesR. T.OsmanA. L., Smokers of Low-yield Cigarettes Do Not Consume Less Nicotine, N. Engl. J. Med.309, pp. 139–142, 1983.
26.
HenningfieldJ. E., Behavioral Pharmacology of Cigarette Smoking, in Advances in Behavioral Pharmacology (Vol. IV), ThompsonT.DewsP. B. (eds.), Academic Press, New York, 1984.
27.
HenningfieldJ. E., Pharmacologic Basis and Treatment of Tobacco Dependence, J. Clin. Psychi, 45, pp. 24–34, 1984.
28.
BenowitzN. L.JacobP.SavanapridiC., Determinants of Nicotine Intake while Chewing Nicotine Polacrilex, Clin. Pharma. and Therap, 41, pp. 467–473, 1987.
29.
HenningfieldJ. E.GolbergS. R., Stimulus Properties of Nicotine in Animals and Human Volunteers: A Review, Behavioral Pharmacology, pp. 433–449, 1984.
30.
RosecransJ. A.MeltzerL. T., Central Sites and Mechanisms of Action of Nicotine, Neurosci. Biobehav. Rev., 5, pp. 497–501, 1981.
31.
HenningfieldJ. E.MiyasatoK.JasinskiD. R., Abuse Liability and Pharmacodynamic Characteristics of Intravenous and Inhaled Nicotine, J. Pharmacol. Exp. Ther., 234, pp. 1–12, 1985.
32.
GilbertD. G.WelserR., Emotion, Anxiety, and Smoking, in Smoking and Human Behavior, NeyT.GayleT. (eds.), John Wiley, London, (in press).
33.
PomerleauO. F.PomerleauC. S., Neuroregulators and the Reinforcement of Smoking: Towards a Biobehavioral Explanation, Neurosci. Biobehav. Rev.8, pp. 530–513, 1984.
34.
HenningfieldJ. E.GolbergS. R., Nicotine as a Reinforcer in Human Subjects and Laboratory Animals, Pharmacol. Biochem. Behav., 19, pp. 989–992, 1983.
35.
GritzE. R., Smoking Behavior and Tobacco Abuse, in Advances in Substance Abuse, MelloN. K. (ed.), JAI Press, Greenwich, Connecticut, 1980.
36.
SchacterS., Studies of the Interaction of Psychological and Pharmacological Determinants of Smoking, J. Exp. Psychol., 6, pp. 3–40, 1977.
37.
LucchesiB. R.SchusterC. R.EmleyG. S., The Role of Nicotine as a Determinant of Cigarette Smoking Frequency in Man with Observations of Certain Cardiovasculars Effects Associated with Tobacco Alkaloid, Clin. Pharmacol. Ther., 8, 1967.
38.
SchacterS., Nicotine Regulation in Heavy and Light Smokers, J. Exp. Psychol., 6, p. 1, 1977.
39.
BrecherE. M., Licit and Illicit Drugs, Little Brown and Company, Boston1972.
40.
PechacekT. F.MurrayD. M.LuepkerR. V.MittlemarkM. B.JohnsonC. A.ShutzJ. M., Measurement of Adolescent Smoking Behavior: Rationale and Methods, J. Behav. Med., 7, pp. 123–140, 1984.
41.
LangleyJ. H.DickinsonW. L., On the Local Paralysis of the Peripheral Ganglia and on the Connexion of Different Classes of Nerve Fibres with Them, Proceeding of the Royal Society, 46, pp. 423–431, 1889.
42.
HughesJ. R.HatsukamiD., Signs and Symptoms of Tobacco Withdrawal, Arch. Gen. Psychiatry, 43, pp. 289–294, 1986.
43.
HatsukamiD. K.GustS. W.KeenanR. M., Physiologic and Subjective Changes from Smokeless Tobacco Withdrawal, Clin. Pharma. and Therapeutics, 41:1, pp. 103–107, 1987.
44.
WestR. J., Psychology and Pharmacology in Cigarette Withdrawal, J. Psychosom. Res., 28, pp. 379–386, 1984.
45.
SchumakerS. A.GrunbergN. E., (eds.) Proceedings of the National Working Conference on Smoking Relapse, Health Psychol., 5, (Supplement), 1986.
46.
SchroederK. L.IsaderosaG. B.ChenM. S.Jr.BabushkinJ. A., Relationship of Nicotine Consumption to Smokeless Tobacco Habits and Health Attitudes, J. Dent. Res. (Special Issue) 65, p. 1364, 1986.
47.
SchroederK. L.IaderosaG. B.ChenM. S.Jr.GloverE. D.EdmundsonE. W., Biomodal Initiation of Smokeless Tobacco Usage: Implications for Cancer Education, J. Can. Educ., 2:1, pp. 1–7, 1987.
48.
GloverE. D.JohnsonR.LaflinM.EdwardsS. W.ChristenA. G., Smokeless Tobacco Use Trends among College Students in the United States, World Smoking and Health, 11:1, pp. 4–9, 1986.
49.
GloverE. D., Modeling — A Powerful Change Agent, J. Sch. Health, 48, pp. 175–176, 1978.
50.
MartyP. J.McDermottR. J.WilliamsT., Patterns of Smokeless Tobacco Use in a Population of High School Students, Am. J. Public Health, 76, pp. 190–192, 1986.
51.
SchaeferS. P.HendersonA. H.GloverE. D.ChristenA. G., Patterns of Use and Incidence of Smokeless Tobacco Consumption in School-aged Children, Arch. Otolaryngol., 111, pp. 639–642, 1985.
52.
McDermottR. J.MartyP. J., Dipping and Chewing Behavior among University Students: Prevalence and Patterns of Use, J. Sch. Health, 56:5, pp. 170–175, 1986.
53.
WilliamsT.GuytonR.MartyP. J.McDermottR. J.YoungM. E., Smokeless Tobacco Use among Rural High School Students in Arkansas, J. Sch. Health, 56:7, pp. 282–285, 1986.
54.
ConnollyG. N.WinnD. M.HechtS. S.HenningfieldJ. E.HoffmanD.WalkerB., The Reemergence of Smokeless Tobacco, N. Engl. J. Med.314:116, pp. 1020–1027, 1986.
55.
ChristenA. G., The Case Against Smokeless Tobacco: Five Facts for the Health Professional to Consider, J. Am. Dent. Assoc., 101, pp. 464–469, 1980.
56.
SchroederK. L.ChenM. S.Jr.KuthyR. A., Smokeless Tobacco: The New Thing to Chew On, Ohio Dent. J., 59, pp, 11–14, 1985.
57.
LindemeyerR. G.BaumR. H.HsuS. C.GoingR. E., In Vitro Effects of Tobacco on the Growth of Oral Cariogenic Streptococci, J. Am. Dent. Assoc.193, pp. 719–722, 1981.
58.
GreerR. O.Jr.PoulsonT. C., Oral Tissue Alterations Associated with the Use of Smokeless Tobacco by Teenagers. Part 1. Clinical findings, Oral Surg. Oral Med. Oral Pathol., 56, pp. 275–284, 1983.
59.
FrithiofL.AnnerothG.LassonU.SederholmC., The Snuff-induced Lesion. A Clinical and Morphological Study of a Swedish Material, Acta Ondontol. Scand., 41, pp. 53–64, 1983.
60.
CullenJ. W.BlotW.HenningfieldJ.BoydG.MecklenburgR.MasseyM. M., Health Consequences of Using Smokeless Tobacco: Summary of the Advisory Committee's Report to the Surgeon General, Public Health Reports, 101:4, pp. 355–373, 1986.
61.
SeversonH.LichtensteinE.GallisonC., A Pinch Instead of a Puff? Implications of Chewing Tobacco for Addictive Processes, Bull. Soc. Psych. Addict. Behav., 4, pp. 85–92, 1985.
62.
OffenbacherS.WeathersD. R., Effects of Smokeless Tobacco on the Periodontal, Mucosal and Caries Status of Adolescent Males, J. Oral Pathol., 14, pp. 169–181, 1985.
63.
Roed-PetersonB.PindborgJ. J., A Study of Danish Snuff-induced Oral Leukoplakia, J. Oral Pathol., 2, pp. 301–313, 1973.
64.
SilvermanS.BhargavaK.ManiN. J.SmithL. W.MalaowallaA. M., Malignant Transformation and Natural History of Oral Leukoplakia in 57, 518 Industrial Workers of Gujarat, India, Cancer, 41, pp. 1790–1795, 1976.
65.
MehtaF. S.GuptaP. C.PinborgJ. J., Chewing and Smoking Habits in Relation to Precancer and Oral Cancer, J. Cancer Res. Clin. Oncol., 99, pp. 35–39, 1981.
66.
Van WykC. W., The Oral Lesion Caused by Snuff, J. Dent. Assoc. S. Afr, 21, pp. 109–116, 1966.
67.
PoulsonT. C., Al Changes in Juvenile, Adult and Geriatric Patients: Clinical and Histomorphological fn Teenagers, CA, 34, pp. 248–261, 1984.
68.
SquiresW. G.BrandonT. A.ZinkgrafS.BondsD.HartungG. H.MurrayT.JacksonA. S.MillerR. R., Hemodynamic Effects of Oral Smokeless Tobacco in Dogs and Young Adults, Prev. Med., 13, pp. 195–206, 1984.
69.
BordiaA.PurbiyaS. L.KhabyaB. L.AroraS. K.HatimiI. H.SinghS. V., A Comparative Study of Common Modes of Tobacco Use on Pulse, Blood Pressure, Electrocardiogram and Blood Coaguability in Patients with Coronary Artery Disease, J. Assoc. Physicians India, 25, pp. 395–401, 1977.
70.
BlachleyJ. D.KnochelJ. P., Tobacco Chewer's Hypokalemia: Licorice Revisited, N. Engl. J. Med., 302, pp. 784–785, 1980.
71.
BenowitzN. J.KuytF.PeytonJ., Influences of Nicotine on Cardiovascular and Hormonal Effects of Cigarette Smoking, Clin. Pharmacol. Ther., 36, pp. 74–81, 1984.
72.
McPhaulM.PunziH.SandyA.BorganelliM.RudeR.KaplanN., Snuff-induced Hypertension in Pheochromocytoma, JAMA252, pp. 2860–2862, 1984.
73.
BelletS.WestJ. M.MullerO. F.ManzoliV. C., Effect of nicotine on the Coronary Blood Flow and Related Circulatory Parameters, Circulation Res., 10, pp. 27–34, 1962.
74.
RussellM. A. H.JarvisM. J.FeyerabendC., A New Age for Snuff, Lancet, 1, pp. 474–475, 1980.
75.
KiserJ. C.BooherW. T.WattsD. T., Blood Epinephrine Levels in Dogs Following the Intravenous Administration of Nicotine, Arch. Int. Pharmacodyn. Ther., 3, pp. 403–411, 1956.
76.
GloverE. D.EdwardsS. W.ChristenA. G.FinnicumP., Smokeless Tobacco Research: An Interdiscliplinary Approach, Health Values, 8, pp. 21–25, 1984.
77.
SchroederK. L.ChenM. S.Jr., Smokeless Tobacco and Blood Pressure, N. Engl. J. Med., 312, p. 919, 1985.
78.
EdwardsS. W.GloverE. D., Snuff and Neuromuscular Performance, Am. J. Public Health, 76, p. 206, 19xx.
79.
PattenB. M., Neuromuscular Disease Due to Tobacco Use, Tex. Med., 80, pp. 47–51, 1984.
