Non-invasive neuroimaging plays a crucial role in the assessment of the human spinal cord, but it is quite challenging. Magnetic resonance imaging (MRI) is an important modality to obtain both high-resolution anatomical and functional information concerning the spinal cord. Besides conventional MRI, advanced MRI techniques could provide novel information about the microstructure and neural function of the spinal cord, thereby enhancing the understanding of spinal cord neurology and pathology of various spinal disorders.
HeB., ColemanT., GeninG.M., GloverG., HuX., JohnsonN., LiuT., MakeigS., SajdaP., YeK.Grand challenges in mapping the human brain: NSF workshop report. IEEE Trans Biomed Eng2013, 60(11): 2983–2992.
2.
UludağrK., RoebroeckA.General overview on the merits of multimodal neuroimaging data fusion. NeuroImage2014, 102(Pt 1): 3–10.
3.
StromanP.W., Wheeler-KingshottC., BaconM., SchwabJ.M., BosmaR., BrooksJ., CadotteD., CarlstedtT., CiccarelliO., Cohen-AdadJ.The current state-of-the-art of spinal cord imaging: Methods. NeuroImage2014, 84: 1070–1081.
4.
MartinA.R., AleksanderekI., Cohen-AdadJ., TarmohamedZ., TetreaultL., SmithN., CadotteD.W., CrawleyA., GinsbergH., MikulisD.J.Translating state-of-the-art spinal cord MRI techniques to clinical use: A systematic review of clinical studies utilizing DTI, MT, MWF, MRS, and fMRI. NeuroImage Clin2016, 10: 192–238.
5.
Wheeler-KingshottC.A., StromanP.W., SchwabJ.M., BaconM., BosmaR., BrooksJ., CadotteD.W., CarlstedtT., CiccarelliO., Cohen-AdadJ.The current state-of-the-art of spinal cord imaging: Applications. NeuroImage2014, 84: 1082–1093.
6.
LiuX.J., ZhouF.Q., LiX., QianW.S., CuiJ.L., ZhouI.Y., LukK.D.K., WuE.X., HuY.Organization of the intrinsic functional network in the cervical spinal cord: A resting state functional MRI study. Neuroscience2016, 336: 30–38.
7.
WangS.Q., LiX., CuiJ.L., LiH.X., LukK.D.K., HuY.Prediction of myelopathic level in cervical spondylotic myelopathy using diffusion tensor imaging. J Magn Reson Imaging2015, 41(6): 1682–1688.
8.
KowalczykI., DuggalN., BarthaR.Proton magnetic resonance spectroscopy of the motor cortex in cervical myelopathy. Brain2012, 135(2): 461–468.
9.
LauleC., VavasourI.M., ZhaoY., TraboulseeA.L., OgerJ., VavasourJ.D., MackayA.L., LiD.K.B.Two-year study of cervical cord volume and myelin water in primary progressive multiple sclerosis. Mult Scler2010, 16(6): 670–677.
10.
Cohen-AdadJ., El MendiliM.M., LehéricyS., PradatP.F., BlanchoS., RossignolS., BenaliH.Demyelination and degeneration in the injured human spinal cord detected with diffusion and magnetization transfer MRI. NeuroImage2011, 55(3): 1024–1033.