We present a 17-year follow-up of an unusual patient with median cleft of the lower lip, mandible, and tongue with a flexion contracture.
Conclusion:
Timing of the mandibular reconstruction needs to take into account growth of the mandible and masticatory function. In this case, fixation of the mandible performed at the age of 6 years 6 months and reconstruction carried out at 7 years 8 months of age resulted in satisfactory occlusion and masticatory function.
ChapmanS., GoldinJ.H., HendelR.G., HockleyA.D., WakeM.C.J., WealeP.. The median cleft face syndrome with associated cleft mandible, bifid odontoid peg and agenesis of the anterior arch of atlas.Br J Oral Maxillofac Surg.1991; 29: 279–281.
3.
ChiY., SasanoY., BringasP., MayoM., KaartinenV., HeisterkampN., GroffenJ., SlavkinH., ShulerC.. Characterization of the fate of midline epithelial cells during the fusion of mandibular prominences in vivo.Dev Dyn.1997; 208: 526–535.
4.
ConstantinidesC.G., CywesS.. Complete median cleft of the mandible and aplasia of the epiglottis.S Afr Med J.1983; 64: 293–294.
5.
DavisA.D.. Median cleft of the lower lip and mandible.Plast Reconstr Surg.1950; 6: 62–67.
6.
EnlowD.H.. The facial growth process, part 2. In: Facial Growth.3rd ed.Philadelphia: WB Saunders; 1990: 77–148.
7.
FujinoH., KyoshoinY., KatsukiT.. Median cleft of the lower lip, mandible, and tongue with midline cervical cord: a case report.Cleft Palate J.1970; 7: 679–684.
8.
GardnerD.G., KapurR.N., JordanR.E.. A cleft of the mandible in the lateral incisor-cuspid region.J Oral Surg.1973; 35: 649–652.
9.
IregbulemL.M.. Median cleft of the lower lip.Plast Reconstr Surg.1978; 61: 787–789.
10.
KnowlesC.C., LittlewoodA.H.M., BushP.G.. Incomplete median cleft of the lower lip and chin with complete cleft of the mandible.Br Dent J.1969; 127: 337–339.
11.
LekkasC., LatiefB.S., CorputtyJ.E.M.. Median cleft of the lower lip associated with lip pits and cleft of the lip and palate.Cleft Palate Craniofac J.1998; 35: 269–271.
12.
MillardD.R., LehmanJ.A., DeaneM., GarstW.P.. Median cleft of the lower lip and mandible: a case report.Br J Plast Surg.1971; 24: 391–395.
13.
MillardD.R., WolfeS.A., BerkowitzS.. Median cleft of the lower lip and mandible: correction of the mandibular defect.Br J Plast Surg.1979; 32: 345–347.
14.
MonroeC.W.. Midline cleft of the lower lip, mandible and tongue with flexion contracture of the neck: case report and review of the literature.Plast Reconstr Surg.1966; 35: 312–319.
15.
MortonC.B., JordanH.E.. Median cleft of lower lip and mandible, cleft sternum and absence of basihyoid.Arch Surg.1935; 30: 647–656.
16.
OostromC.A.M., Vermeij-KeersC., GilbertP.M., van der MeulenJ.C.. Median cleft of the lower lip and mandible: case reports, a new embryologic hypothesis, and subdivision.Plast Reconstr Surg.1996; 97: 313–320.
17.
RantaR.. Incomplete median cleft of the lower lip associated with cleft palate, the Pierre Robin anomaly or hypodontia.Int J Oral Surg.1984; 13: 555–558.
18.
RaoS., OakS., WaghM., KulkarniB.. Congenital midline palatomandibular bony fusion with a mandibular cleft and a bifid tongue.Br J Plast Surg.1997; 50: 139–141.
19.
Richieri-CostaA., PereiraS.C.S.. Autosomal recessive short stature, Robin sequence, cleft mandible, pre/postaxial hand anomalies, and clubfeet in male patients.Am J Med Genet.1993; 47: 707–709.
20.
Richieri-CostaA., PereiraS.C.S.. Short stature, Robin sequence, cleft mandible, pre/postaxial hand anomalies, and clubfoot: a new autosomal recessive syndrome.Am J Med Genet.1992; 42: 681–687.
21.
ShermanJ.E., GoulianD.. The successful one-stage surgical management of a midline cleft of the lower lip, mandible, and tongue.Plast Reconstr Surg.1980; 66: 756–759.
22.
StewartW.J.. Congenital median cleft of the chin.Arch Surg.1935; 31: 813–815.
23.
SurendranN., VargheseB.. Midline cleft of lower lip with cleft of the mandible and midline dermoid in the neck.J Pediatr Surg.1991; 26: 1387–1388.
24.
WeinbergS., MoncarzV., Van de MarkT.B.. Midline cleft of the mandible: review of literature and report of case.J Oral Surg.1972; 30: 143–148.