To evaluate the efficiency of 2 distal filtration devices designed for cerebral protection during carotid angioplasty in an in-vitro bench-top model.
Methods:
After positioning the respective protection devices (RX Accunet and DynaCap) 5 cm distal to the bifurcation, embolization from carotid angioplasty was simulated by injecting polyvinyl alcohol particles in groups of small (150 to 250-μm diameter, ~500 particles), medium (250 to 355-μm diameter, ~200 particles), and large (700 to 1000-μm diameter, ~80 particles). Five milligrams of each group were injected separately into the internal carotid artery (ICA) model proximal to the protection filters. Particles passing the protection devices were caught in 100-μm filters and weighed.
Results:
For small particles, the amount in the effluent of the ICA was 0.34±0.12 mg (6.8%) for the RX Accunet and 0.51±0.16 mg (11.2%) for the Occam DynaCap (p<0.05). For the other particle sizes, there was no statistical difference between the filters (p>0.05).
Conclusion:
In all test runs, neither of the tested devices prevented embolization completely, with ~3% to 6% of particles penetrating. For small particles, the lowest amount of particles passing the protection device was achieved using the RX Accunet system.
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