Tenosynovial giant cell tumor (TGCT) is a benign proliferative lesion of unclear etiology. It is predominantly monoarticular and involves the synovium of the joint, tendon sheath, and bursa. TGCT of the temporomandibular joint (TMJ) is rare and aggressive resulting in destruction of surrounding structures. The diagnosis may be suggested by imaging, mainly by the MR features and PET/CT, and confirmed by histopathology. We describe the case of a 50-year-old man who presented with right-sided hearing loss, tinnitus and TMJ pain. Pathology revealed tenosynovial giant cell tumor with chondroid metaplasia. Six years later he developed a recurrence, which was documented to our knowledge for the first time with CT, MR and FDG PET/CT imaging.
FletcherCDMBridgeJAHogendornPCW. World Health Organization classification of tumours of soft tissue and bone. Lyon: International Agency for Research on Cancer (IARC) Press; 2013.
2.
RomañachMJBrasileiroBFLeónJE. Pigmented villonodular synovitis of the temporomandibular joint: Case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod.2011; 111 (3): e1728. doi: 10.1016/j.tripleo.2010.11.019.
3.
TosunFCarrauRLWeissmanJ. Pigmented villonodularsynovitis of the temporomandibular joint: An extensive case with skull-base involvement. Am J Otolaryngol.2004; 25 (3): 204–207. doi: 10.1016/j.amjoto.2003.11.006.
4.
DayJDYooAMuckleR. Pigmented villonodular synovitis of the temporomandibular joint: a Rare tumor of the temporal skull base. J Neurosurg.2008; 109 (1): 140–143. doi: 10.3171/JNS/2008/109/7/0140.
5.
HermanCRSwiftJQSchiffmanEL. Pigmented villonodular synovitis of the temporomandibular joint with intracranial extension: a Case and literature review. Int J Oral Maxillofac Surg.2009; 38 (7): 795–801. doi: 10.1016/j.ijom.2009.02.013.
6.
CaiJCaiZGaoY. Pigmented villonodularsynovitis of the temporomandibular joint: a Case report and the literature review. Int J Oral Maxillofac Surg.2011; 40 (11): 1314–1322. doi: 10.1016/j.ijom.2011.03.003.
7.
LiuYChanJChangC. Pigmented villonodular synovitis of the temporomandibular joint presenting as a middle cranial fossa tumor. J Oral Maxillofac Surg.2012; 70 (2): 367–372. doi: 10.1016/j.joms.2011.02.031.
8.
YoonHJChoYALeeJI. Malignant pigmented villonodularsynovitis of the temporomandibular joint with lung metastasis: a Case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod.2011; 111 (5): e3036. doi: 10.1016/j.tripleo.2010.11.031.
9.
KimKWHanMHParkSW. Pigmented villonodularsynovitis of the temporomandibular joint: MR findings in four cases. Eur J Radiol.2004; 49 (3): 229–234. doi: 10.1016/S0720-048X(03)00099-8.
LeeJHKimYYSeoBM. Extra-articular pigmented villonodular synovitis of the temporomandibular joint: Case report and review of the literature. Int J Oral Maxillofac Surg.2000; 29 (6): 408–415. doi: 10.1034/j. 1399–0020.2000.290603.x.
12.
KitapciMTColemanRE. Incidental detection of pigmented villonodular synovitis on FDG PET. Clin Nucl Med.2003; 28 (8): 668–669. doi: 10.1097/01.rlu.0000079430.82897.b8.
13.
HochBLGarciaRASmalbergerGJ. Chondroid tenosynovial giant cell tumor: a Clinicopathological and immunohistochemical analysis of 5 new cases. Int J Surg Pathol.2011; 19 (2): 180–187. doi: 10.1177/1066896910381899.
14.
O'ConnellJXFanburgJCRosenbergAE. Giant cell tumor of tendon sheath and pigmented villonodular synovitis: Immunophenotype suggests a synovial cell origin. Hum Pathol.1995; 26 (7): 771–775. doi: 10.1016/0046-8177(95)90226-0.
15.
CaiXYYangCChenMJ. Simultaneous pigmented villonodular synovitis and synovial chondromatosis of the temporomandibular joint: Case report. Int J Oral Maxillofac Surg.2009; 38 (11): 1215–1218. doi: 10.1016/j.ijom.2009.06.014.
