The dynamic behavior of a musculoskeletal link system in manual lifting is simulated by a mathematical model which contains a non-linear objective function and a set of linear, as well as non-linear constraints. The model was developed based upon the hypothesis that an individual performs the lifting motion following the principle of minimizing mechanical work done. The simulation model demonstrated that the associated differences between the predicted motion and the measured motion is biomechanically feasible and the accuracy is adequate enough with an average U statistics ranging from 0.012 to 0.2 09.
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