Abstract
Inhaled particles smaller than 4 μm can cause damage to lung tissue, a disease called silicosis. We present an investigation on the use of a Raman microspectrometer for the identification of inclusions in lung tissue. We measured Raman spectra of such inclusions in lung tissue of a patient whose probable cause of death was silicosis. Most of the inclusions we could identify were calcite particles.
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References
1.
Heinrich
K. F. J.
, in Proc. Scanning Electron Microscopy Symp. ,
Johari
O.
, Ed. (Chicago , Illinois , 1977 ), p. 605 .
2.
Delhaye
M.
and
Dhamelincourt
P.
, J. Raman Spect. 3 , 33 (1975 ).
3.
Rosasco
G. J.
and
Etz
E. S.
, Res./Dev. 28 , 20 (1977 ).
4.
Etz
E. S.
Rosasco
G. J.
, and
Cunningham
W. C.
, in Environmental Analysis ,
Ewing
G. W.
, Ed. (Academic Press , New York , 1977 ), p. 295 .
5.
Abraham
J. L.
and
Etz
E. S.
, Science 206 , 716 (1979 ).
6.
Griffith
W. P.
, in Infrared and Raman Spectroscopy of Lunar and Terrestral Minerals ,
Karr
C.
Jr.
, Ed. (Academic Press , New York , 1975 ), Chap. 12, p. 299 .
7.
Rutt
H. N.
and
Nicola
J. H.
, J. Phys. C 7 , 4522 (1974 ).
8.
Krishnamurti
D.
, Proc. Indian Acad. Sci. Sect. A 53 , 210 (1956 ).
9.
Lankester
J.
, personal communication .
10.
de Mul
F. F. M.
Buiteveld
H.
Lankester
J.
Mud
J.
, and
Greve
J.
, “Application of Raman Microscopy in Human Pathology,” submitted to Journal of Human Pathology .