Calibration Transfer of Chemometric Models Based on Process Nuclear Magnetic Resonance Spectroscopy

Abstract

This paper establishes the protocol for calibration transfer of partial least-squares (PLS) regression models between process nuclear magnetic resonance (NMR) spectrometers. The ability to transfer calibration models between instruments allows the addition of new instruments and the upgrade of old instruments with little financial or manpower investment. It will also allow development of calibration for an on-line system on a lab system, which will require less manpower and no down time for the on-line measurements. This capability will result in great cost savings for a production facility where even a minor interruption in the plant operations would result in great loss of production and loss of income.