Abstract
2006 marks the 40th year of publication for The Annals. Over that time, The Annals has been an important contributor to the development of clinical pharmacy, with the journal's founder and first editor, Dr. Don E Francke, exerting a profound influence on the evolution of the profession of pharmacy. Throughout 2006, we will publish articles authored by practitioners, including those pioneering clinical pharmacy, as well as those who have more recently entered the profession and a well-established specialty. Donald C McLeod, the first chairman of the Editorial Board for The Annals, presents the initial article of the series in this issue. Edward Hartshorn, one of the first to recognize the significant impact of drug interactions on pharmacotherapy, also offers his memories of the early days of the journal and how clinical pharmacy has grown (see page 112).
In addition, we are also presenting editorials from the early history of The Annals that have given direction and shape to the practice of clinical pharmacy (see pages 114-22).
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