Abstract
Get full access to this article
View all access options for this article.
References
1.
Walczyk
H
,
Liu
CH
,
Alafris
A
,
Cohen
H.
Probable tapentadol-associated serotonin syndrome after overdose . Hosp Pharm . 2016 ;51 (4) :320 -327 .
2.
Boyer
EW
. Management of opioid analgesic overdose . N Engl J Med . 2012 ;367 (2) :146 -155 .
3.
Raffa
RB
,
Buschmann
H
,
Christoph
T
, Mechanistic and functional differentiation of tapentadol and tramadol . Expert Opin Pharmacother . 2012 ;13 (10) :1437 -1449 .
4.
Dunkley
EJ
,
Isbister
GK
,
Sibbritt
D
,
Dawson
AH
,
Whyte
IM
. The Hunter Serotonin Toxicity Criteria: Simple and accurate diagnostic decision rules for serotonin toxicity . QJM . 2003 ;96 (9) :635 -642 .
5.
Ryan
NM
,
Isbister
GK
. Tramadol overdose causes seizures and respiratory depression but serotonin toxicity appears unlikely . Clin Toxicol (Phila) . 2015 ;53 (6) :545 -550 .
6.
Buckley
NA
,
Dawson
AH
,
Isbister
GK
. Serotonin syndrome . BMJ . 2014 ;348 :g1626.
7.
Isbister
GK
,
Buckley
NA
. Therapeutics in clinical toxicology: In the absence of strong evidence how do we choose between antidotes, supportive care and masterful inactivity . Br J Clin Pharmacol . 2016 ;81 (3) :408 -411 .