Unusual Findings in Persistent Hyperplastic Primary Vitreous: Two Cases

Abstract

Persistent hyperplastic primary vitreous is a result of failure of regression of the embryonic hyaloid artery and presents commonly as leucocoria in the first few weeks of life. It leads to abnormal lenticular development and secondary changes in the retina and orbit. We discuss two cases of persistent hyperplastic primary vitreous with unusual findings. The first case is an example of unilateral involvement, and on high frequency ultrasound, the commonly associated retrolental mass was absent. The hyaloid artery was well visualized on colour and spectral Doppler. The second case had bilateral retrolenticular masses. The hyaloid artery could be demonstrated in one side on colour Doppler. Thickening of the choroido-retinal layer was noted in both sides. Retinal detachment or vitreous haemorrhages, which are commonly associated findings with persistent hyperplastic primary vitreous, were not seen in either case.