Abstract
Pellagra is a disease of poverty that is treatable but easily overlooked. The disease is caused by a deficiency of niacin and is clinically characterized by the triad of dermatitis, diarrhoea and dementia. We describe two cases of pellagra in a Malawian district hospital and discuss the pathogenesis, clinical manifestations and treatment of the disease.
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References
1.
Hegyi
J
Schwartz
RA
Hegyi
V
. Pellagra: dermatitis, dementia and diarrhea . Int J Dermatol
2004 ;43 :1 –5
2.
Darvay
A
Basarab
T
McGregor
JM
Isoniazid induced pellagra despite pyridoxine supplementation . Clin Exp Dermatol
1999 ;24 :167 –9
3.
Okan
G
Yaylaci
S
Alzafer
S
. Pellagra: will we see it more frequently?
J Eur Acad Dermatol Venereol
2009 ;23 :365 –6
4.
Monteiro
JP
da Cunha
DF
Filho
DC
Niacin metabolite excretion in alcoholic pellagra and AIDS patients with and without diarrhea . Nutrition
2004 ;20 :778 –82
5.
Kimokoti
RW
Hamer
DH
. Nutrition, health, and aging in sub-Saharan Africa . Nutr Rev
2008 ;11 :611 –23
