We evaluated the prevalence of vitamin D deficiency in the antenatal patients attending North Middlesex University Hospital between March 2008 and March 2009.
Study design
A prospective study of maternal levels of vitamin D at booking.
Results
The prevalence of both deficient and insufficient levels of 25[OH]D was 87.6% across all included patients.
Conclusion
There is a high prevalence of asymptomatic vitamin D deficiency in the antenatal booking population.
LapillonneA. Vitamin D deficiency during pregnancy may impair maternal and fetal outcomes. Med Hypotheses2010;74:71–5
2.
CamadooL, TibbottR, IsazaF. Maternal vitamin D deficiency associated with neonatal hypocalcaemic convulsions. Nutr J2007;6:23
3.
PascoJA, WarkJD, CarlinJB, PonsonbyAL, VuillerminPJ, MorleyR. Maternal vitamin D in pregnancy may influence not only offspring bone mass but other aspects of musculoskeletal health and adiposity. Med Hypotheses2008;71:266–9
4.
MasonRS, DiamondTH. Vitamin D deficiency and multicultural Australia. Med J Aust2001;175:236–7
5.
GroverSR, MorleyR. Vitamin D deficiency in veiled or dark-skinned pregnant women. Med J Aust2001;175:251–2
6.
DavisLM, ChangSC, ManciniJ, NathansonMS, WitterFR, O'BrienKO. Vitamin D insufficiency is prevalent among pregnant African American adolescents. J Pediatr Adolesc Gynecol2010;23:45–52
7.
BodnarLM, SimhanHN, PowersRW, FrankMP, CoopersteinE, RobertsJM. High prevalence of vitamin D insufficiency in black and white pregnant women residing in the northern United States and their neonates. J Nutr2007;137:447–52
8.
DijkstraSH, van BeekA, JanssenJW, High prevalence of vitamin D deficiency in newborn infants of high risk mothers. Arch Dis Child2007;92:750–3
9.
JudkinsA, EagletonC. Vitamin D deficiency in pregnant New Zealand women. N Z Med J2006;119:U2144
10.
BowyerL, Catling-PaullC, DiamondT, HomerC, DavisG, CraigME. Vitamin D, PTH and calcium levels in pregnant women and their neonates. Clin Endocrinol (Oxf)2009;70:372–7
11.
NicolaidouP, HatzistamatiouZ, PapadopoulouA, Low vitamin D status in mother-newborn pairs in Greece. Calcif Tissue Int2006;78:337–42
12.
SereniusF, ElidrissyAT, DandonaP. Vitamin D nutrition in pregnant women at term and in newly born babies in Saudi Arabia. J Clin Pathol1984;37:444–7
13.
Office for National Statisics. See http://neighbourhood.statistics.gov.uk (last checked 11 July 2011)
14.
15.
HypponenE, PowerC. Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors. Am J Clin Nutr2007;85:860–8
16.
ZeghoudF, VervelC, GuillozoH, Walrant-DebrayO, BoutignonH, GarabedianM. Subclinical vitamin D deficiency in neonates: definition and response to vitamin D supplements. Am J Clin Nutr1997;65: 771–8
17.
SharmaS, KhanN, KhadriA, Vitamin D in pregnancy – time for action: a paediatric audit. BJOG2009;116:1678–82
18.
YuCK, SykesL, SethiM, TeohTG, RobinsonS. Vitamin D deficiency and supplementation during pregnancy. Clin Endocrinol (Oxf)2009;70:685–90. Epub 2008 Sep 2
19.
KovacsCS. Vitamin D in pregnancy and lactation: maternal, fetal, and neonatal outcomes from human and animal studies. Am J Clin Nutr2008;88:p520S–8S
20.
PawleyN, BishopNJ. Prenatal and infant predictors of bone health: the influence of vitamin D. Am J Clin Nutr2004;80:1748S–51S
21.
ThomsonK, MorleyR, GroverSR, ZacharinMR. Postnatal evaluation of vitamin D and bone health in women who were vitamin D-deficient in pregnancy, and in their infants. Med J Aust2004;181: 486–8
