Gitelman's syndrome is a rare genetic disease associated with chronic hypokalaemia, hypomagnesaemia and hypocalciuria. It requires lifelong supplementation with potassium and magnesium. Pregnancy management can be difficult and there are few published reports. Our case adds to the literature and illustrates some of the potential problems.
ShaerAJ. Inherited primary renal tubular hypokalemic alkalosis: a review of Gitelman and Bartter syndromes. Am J Med Sci2001;36:310–3
2.
BasuA, DillonRDS, TaylorR, DavidsonJM, MarshallSM. Is normalisation of serum potassium and magnesium always necessary in Gitelman syndrome for a successful obstetric outcome?BJOG2004;111:630–4
3.
McCarthyFP, MageeCN, PlantWD, KennyLC. Gitelman's syndrome in pregnancy: case report and review of the literature. Nephrol Dial Transpl2010;25:1338–40
4.
SrinivasSK, SukhanS, ElovitzMA. Nausea, emesis and muscle weakness in a pregnant adolescent. Obstet Gynecol2006;107:481–4
5.
DaskalakisG, MarinopoulosS, MousiolisA, MesogitisS, PapantoniouN, AntsaklisA. Gitelman syndrome-associated severe hypokalemia and hypomagnesemia: case report and review of the literature. J Matern Fetal Neonatal Med2010;23:1301–4
6.
De HaanJ, GeersT, BerghputA. Gitelman syndrome in pregnancy. Int J Gynaecol Obstet2008;103:69–71
7.
De ArribaG, Sanchez-HerasM, BasterrecheaMA. Gitelman syndrome during pregnancy: a therapeutic challenge. Arch Gynecol Obstet2009;280:807–9
8.
JonesJM, DorrellS. Outcome of two pregnancies in a patient with Gitelman's syndrome – a case report. J Matern Fetal Invest1998;8:147–8
9.
ShanbhagS, NeilJ, HowellC. Anaesthesia for caesarean section in a patient with Gitemaln's syndrome. Int J Obstet Anesth2010;19:451–3
