We report a case of Kaposi's sarcoma (KS) in an HIV-negative man who has sex with men (MSM) that was successfully treated by topical application of imiquimod 5% cream (Aldara). Our case highlights a potentially effective and non-invasive method of treatment of Kaposi's sarcoma in the shortest timeframe yet recorded. The location of the lesions on the patient's penis also highlights the need for a non-invasive treatment.
JakobL, MetzlerG, ChenKM, GarbeC.Non-AIDS associated Kaposi's sarcoma: clinical features and treatment outcome.PLoS ONE2011; 6: e8397.
2.
UldrickTS, WhitbyD. Update on KSHV epidemiology, Kaposi Sarcoma pathogenesis, and treatment of Kaposi Sarcoma.Cancer Lett305: 150–62
3.
CasperC, WaldA, PaukJ, TabetSR, CoreyL, CelumCL.Correlates of prevalent and incident Kaposi's sarcoma-associated herpesvirus infection in men who have sex with men.J Infect Dis2002; 185: 990–3.
4.
CasperC, MeierAS, WaldA, MorrowRA, CoreyL, MoscickiAB.Human herpesvirus 8 infection among adolescents in the REACH cohort.Arch Pediatr Adolesc Med2006; 160: 937–42.
5.
BenomarS, BoutayebS, BenzekriL, ErrihaniH, HassamB.Kaposi's sarcoma responding to topical imiquimod 5% cream: a case report.Cases J2009; 2: 7092
GoirizR, Rios-BucetaL, De ArribaAG, AraguesM, Garcia-DiezA.Treatment of classic Kaposi's sarcoma with topical imiquimod.Dermatol Surg2009; 35: 147–9.
8.
Celestin SchartzNE, ChevretS, PazC.Imiquimod 5% cream for treatment of HIV-negative Kaposi's sarcoma skin lesions: a phase I to II, open-label trial in 17 patients.J Am Acad Dermatol2008; 58: 585–91.
9.
LanternierF, LebbeC, SchartzN.Kaposis sarcoma in HIV-negative men having sex with men.AIDS2008; 22: 1163–8.
