Adequate antiretroviral therapy is essential for HIV-positive pregnant women to prevent mother-to-child transmission. We report a small case series of five women receiving raltegravir as part of their antiretroviral regimen during pregnancy.
TownsendCL, Cortina-BorjaM, PeckhamCS. Low rates of mother-to-child transmission of HIV following effective pregnancy interventions in the United Kingdom and Ireland, 2000-2006.AIDS2008; 22: 973–81
2.
WarszawskiJ, TubianaR, Le ChenadecJ. Mother-to-child HIV transmission despite antiretroviral therapy in the ANRS French Perinatal Cohort.AIDS2008; 22: 289–99
3.
JaworskyD, ThompsonC, YudinMH. Use of newer antiretroviral agents, darunavir and etravirine with or without raltegravir, in pregnancy: a report of two cases.Antivir Ther2010; 15: 677–80
4.
McKeownDA, RosenvingeM, DonaghyS. High neonatal concentrations of raltegravir following transplacental transfer in HIV-1 positive pregnant women.AIDS2010; 24: 2416–8
5.
PinnettiC, BaroncelliS, VillaniP. Rapid HIV-RNA decline following addition of raltegravir and tenofovir to ongoing highly active antiretroviral therapy in a woman presenting with high-level HIV viraemia at week 38 of pregnancy.J Antilmicrob Chemother2010; 65: 2050–52
6.
Antiretroviral Pregnancy Registry Steering Committee, editor. Antiretroviral Pregnancy Registry International Interim Report for 1 January 1989 through 31 July 2009.2009
7.
ClarrenSK. Plagiocephaly and torticollis: etiology, natural history, and helmet treatment.J Pediatr1981; 98: 92–5
8.
SteigbigelRT, CooperDA, TepplerH. Long-term efficacy and safety of Raltegravir combined with optimized background therapy in treatment-experienced patients with drug-resistant HIV infection: week 96 results of the BENCHMRK 1 and 2 phase III trials.Clin Infect Dis2010; 50: 605–12
9.
ReadP, KhanP, MandaliaS. When should HAART be initiated in pregnancy to achieve an undetectable viral load? Program and abstracts of the 17th Conference on Retroviruses and Opportunistic Infections, 2010, San Francisco, USA, Abstract 896
10.
TubianaR, Le ChenadecJ, RouziouxC. Factors associated with mother-to-child transmission of HIV-1 despite a maternal viral load <500 copies/mL at delivery: a case-control study nested in the French perinatal cohort (EPF-ANRS CO1)<500 copies/mL at delivery: a case-control study nested in the French perinatal cohort (EPF-ANRS CO1).Clin Infect Dis2010; 50: 585–96
