Mycobacterium avium-intracellulare (MAI) infection in an HIV-positive patient can present shortly after starting antiretroviral therapy, as a result of immune reconstitution inflammatory syndrome (IRIS). We report a case of a 33-year-old woman where MAI presented as an endobronchial tumour due to IRIS. She responded well to standard anti-MAI treatment (rifamycins, macrolide and ethambutol).
MehleME, AdamoJP, MehtaAC, Endobronchial Mycobacterium avium intracellulare infection in a patient with AIDS. Chest1989;96:199–201
2.
ShelburneSA, VisnegarwalaF, DarcourtJ, Incidence and risk factors for immune reconstitution inflammatory syndrome during highly active antiretroviral therapy. AIDS2005;19:399–406
3.
RatnamI, ChiuC, KandalaN-B, EasterbrookPJ. Incidence and risk factors for immune reconstitution inflammatory syndrome in an ethnically diverse HIV type 1-infected cohort. Clin Infect Dis2006;42:418–27
4.
RaceEM, Adelson-MittyJ, KriegelGR, Focal mycobacterial lymphadenitis following initiation of protease-inhibitor therapy in patients with advanced HIV-1 disease. Lancet1998;351:252–5
5.
MurrayR, MallalS, HeathC, FrenchM. Cerebral Mycobacterium avium infection in an HIV patient following immune reconstitution and cessation of therapy for disseminated Mycobacterium avium complex infection. Eur J Clin Microbiol Infect Dis2001;20:199–201
6.
PhillipsP, BonnerS, GataricN, Nontuberculous mycobacterial immune reconstitution syndrome in HIV-infected patients: spectrum of disease and long-term follow-up. Clin Infect Dis2005;41:1483–97. Epub 2005 Oct 12
7.
BartleyPB, AllworthAM, EisenDP. Mycobacterium avium complex causing endobronchial disease in AIDS patients after partial immune restoration. Int J Tuberc Lung Dis1999;3:1132–6
