Abstract
In order to investigate the efficacy of treatment modalities favoured by us against flat acetowhite penile human papillomavirus HPV induced lesions, we studied retrospectively standardized medical records of 81 men who had been treated for this condition. The patients were treated surgically with diathermy n =32 or with a combination of both chemical topical application of podophyllotoxin and surgical treatment n =49 . The mean number of clinic visits was 9.1 range 1-19 , during a follow up time of mean 30.9 range 1-104 months for 78 of the men, 3 of them only visited the clinic once. The mean time for cure was 19.9 range 0-103 months. Only 12 15 patients were healed after one single treatment session, while as many as 50 62 required > 4 sessions. The mean number of surgical treatment sessions required for cure differed significantly P =0.0006 between the previously treated patients who needed a mean of 5.6 treatment sessions, compared to the previously untreated men who required surgery a mean of 3.4 times for cure.
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