Abstract
The predominant mode of HIV-1 transmission globally is from sexual practices. The risk of HIV-1 transmission by sexual means is a function of infectivity, susceptibility and mode of transmission (type of sexual practice). In addition, transmission may be enhanced by the presence of sexually transmissible infections (STIs). An understanding of the interplay between sexual practices, STIs and HIV-1 may facilitate the development of effective treatment and prevention strategies. These topics are the subject of this review.
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