The blood pressure measured directly in the distal part of the central ear artery is dependent upon the degree of vasodilation of the vessel, and exhibits spontaneous variation. This variation is abolished by hexamethonium in doses which had only a minor, transient hypotensive effect. While the degree of ganglionic block could not easily be quantitated, stability of peripheral arterial pressure and heart rate persisted for more than 2 hours.
References
1.
AlexanderN. & DeQuattroV. (1974). Regional and systemic hemodynamic patterns in rabbits with neurogenic hypertension. Circulation Research35, 636-645.
2.
CampbellD. J. & SkinnerS. L. (1973). Cellophane perinephritis hypertension and its reversal in rabbits. Circulation Research33, 105-112.
3.
RomeroJ. C., LazarJ. D. & HooblerS. W. (1970). Effects of renal artery constriction and subsequent contralateral nephrectomy on the blood pressure, plasma renin activity and plasma renin substrate concentrations in rabbits. Laboratory Investigations22, 581-587.
4.
RomeroJ. C., OttC. E., AguiloJ. J., TorresV. E. & StrongC. G. (1975). Role of prostaglandins in the reversal of one-kidney hypertension in the rabbit. Circulation Research37, 683-689.
5.
WestM. J., AngusJ. A. & KornerP. I. (1975). Estimation of non-autonomic and autonomic components of iliac bed vascular resistance in renal hypertensive rabbits. Cardiovascular Research9, 697-706.
6.
WilsonD. M., RomeroJ. C., StrongC. G., LeeK. E. & SchryverS. M. (1975). Indirect blood pressure measurement in the rabbit: correlations with direct aortic and ear pressures. Journal of Laboratory and Clinical Medicine86, 1032-1039.