Substantial interaction was observed in 3 inbred strains of mice maintained on 5 normal commercial pelleted diets. Strain B10.BR was most sensitive to the unknown dietary factor, and the ranking of B10.BR and A2G was reversed across the array of diets. There was no apparent relationship between the ‘biological’ value of the diet and 21 dietary ingredients determined chemically. The study shows that the diet which gives the best performance for one strain of mice may not be the best for another.
References
1.
EleftheriouB. E., EliasM. F., CastellanoC, & OliverioA. (1975). Cortex weight: a genetic analysis in the mouse. Journal of Heredity66, 207-212.
2.
FestingM. F. W. (1976). Effects of marginal malnutrition on the breeding performance of inbred and F1 hybrid mice—a diallel study. In The laboratory animal in the study of reproduction (ed. AntikatzidesT., ErichsenS., & SpiegelA), pp. 99-113. Stuttgart: Fischer.
3.
FreemanG. H. (1973). Statistical methods for the analysis of genotype environment interactions. Heredity, London31, 339-354.
4.
FulkerD. W., WilcockJ. & BroadhurstP. L. (1972). Studies in genotype-environment interactions. I. Methodology and preliminary multivariate analysis of a diallel cross of eight strains of rat. Behavior Genetics2, 261-287.
5.
GreenmanD. L., OllerW. L., LittlefieldN. A. & NelsonC. J. (1980). Commercial laboratory animal diets: toxicant and nutrient variability. Journal of Toxicology and Environmental Health6, 235-246.
6.
HoagW. G. & DickieM. M. (1960). A comparison of five commercial diets in two inbred strains of mice. Proceedings of the Animal Care Panel10, 109-116.
7.
NewberneP. M. (1975). Influence on pharmacological experiments of chemical and other factors in diets of laboratory animals. Federation Proceedings. Federation of American Societies for Experimental Biology34, 209-218.
8.
ParrottR. F. & FestingM. F. W. (1971). Standardized laboratory animals. A guideline to the genetical and microbiologically defined colonies maintained at the Laboratory Animals Centre.Medical Research Council Laboratory Animals Centre, Manual Series 2.
9.
TownsendG. H. (1969). The grading of commercially-bred laboratory animals. Veterinary Record85, 225-226.