The fine structure of rhesus monkey renomedullary interstitial cells was studied by electron microscopy. These stellate cells contained variable numbers of lipid droplets, moderate numbers of mitochondria, moderate amounts of rough endoplasmic reticulum, and prominent Golgi zones. In rare instances, apparent release of lipid droplets into the interstitium was observed. The most prominent feature of the interstitial cells was large nuclear pseudoinclusions which were observed in a high proportion of the animals examined.
References
1.
BennettC. M., BrennerB. M., & BerlinerR. W. (1968). Micropuncture study of nephron function in the rhesus monkey. Journal of Clinical Investigation47, 203215.
2.
BohmanS.-O. (1974). The ultrastructure of the rat renal medulla as observed after improved fixation methods. Journal of Ultrastructure Research47, 329360.
3.
BohmanS.-O., & MaunsbachA. B. (1969). Isolation of the lipid droplets from the interstitial cells of the renal medulla. Journal of Ultrastructure Research29, 569.
4.
BulgerR. E., & TrumpB. F. (1966). Fine structure of the rat renal papilla. American Journal of Anatomy118, 685722.
5.
BulgerR. E., TisherC. C., MyersC. H., & TrumpB. F. (1967). Human renal ultrastructure. II. The thin limb of Henle's loop and the interstitium in healthy individuals. Laboratory Investigation16, 124141.
6.
GhadiallyF. N. (1975). Ultrastructural pathology of the cell.London: Butterworths.
7.
LimasC., LimasC. J., RaganD., & FreisE. D. (1976). Renomedullary interstitial cells in the spontaneously hypertensive rat. Laboratory Investigation34, 606610.
8.
MaunsbachA. B. (1966). The influence of different fixatives and fixation methods on the ultrastructure of rat kidney proximal tubule cells. II. Effects of varying osmolality, ionic strength, buffer system and fixative concentration of glutaraldehyde solutions. Journal of Ultrastructure Research15, 283309.
9.
MuehrckeR. C., MandaiA. K., & VoliniF. I. (1969). Cytoplasmic granularity of the renal medullary interstitial cells in experimental hypertension. Journal of Laboratory and Clinical Medicine73, 299319.
10.
MuirheadE. E., BrownG. B., GermainG. S., & LeachB. E. (1970). The renal medulla as an antihypertensive organ. Journal of Laboratory and Clinical Medicine76, 641651.
11.
MuirheadE. E., GermainG., LeachB. E., PitcockJ. A., StephensonP., BrooksB., BrosiusW. L., & DanielsE. G. (1972). Production of renomedullary prostaglandins by interstitial cells grown in tissue culture. Circulation Research31, 161172.
12.
OsvaldoL., & LattaH. (1966). Interstitial cells of the renal medulla. Journal of Ultrastructure Research15, 589613.
13.
RosenS., & TisherC. C. (1968). Observations on the rhesus monkey glomerulus and juxtaglomerular apparatus. Laboratory Investigation18, 240248.
14.
SobelH. J., SchwarzR., & MarquetE. (1969). Non-viral nuclear inclusions. I. Cytoplasmic invaginations. Archives of Pathology87, 179192.
15.
TisherC. C. (1971). Relationship between renal structure and concentrating ability in the rhesus monkey. American Journal of Physiology220, 11001106.
16.
TisherC. C. (1975). In The rhesus monkey. Structure and function of the rhesus kidney (ed. BourneG. H.), vol. 1, chap. 4. New York: Academic Press.
17.
TobianL., IshiiM., & DukeM. (1969). Relationship of cytoplasmic granules in renal papillary interstitial cells to 'postsalt' hypertension. Journal of Laboratory and Clinical Medicine73, 309319.
18.
TrumpB. F., & ArstilaA. U. (1975). Cellular reaction to injury. In Principles of pathobiology (ed. La ViaM. F., & HillR. B.). Oxford: Oxford Medical Publications.
19.
WoodardJ. C. (1968). Reply to letter on nuclear inclusions. Archives of Pathology85, 568.