Fractional extracellular space and fractional water content of various rat tissues at different extracellular pH values and in uremia

Abstract

Summary

At different extracellular pH values fractional extra-cellular space (calculated from the distribution of ³H inulin) and fractional water content showed no significant differences. 72 h after nephrectomy both variables increased significantly. An exception to this was brain, where fractional extracellular space decreased and total intracellular water increased as a sign of brain oedema.