Abstract
The introduction of mice free from lymphocytic choriomeningitis (LCM) necessitated a rigorous program of elimination of LCM-infected mice, followed by disinfection and rodent-proofing of buildings. The program was phased to ensure a continuing supply of experimental mice to the laboratory.
The maintenance of the LCM-free colony, including strict hygienic precautions such as the wearing of protective clothing and the disinfection of food, bedding and equipment, is described.
The value of LCM-free mice in laboratory work and the use of the colony in testing other laboratory and wild rodents for LCM are briefly discussed.