Abstract
Streptococcal infections were diagnosed in a group of strain 2 guinea-pigs. 10 of the animals had cervical lymphadenitis with abscess formation. Other lesions noted were: widespread lymphadenitis, pericarditis, myocardial degeneration, peritonitis, pleuritis, and chronic nephritis. It was not proved that the nephritis was a result of the streptococcal infection, although a relationship was inferred. Chains of gram-positive cocci were seen in lymph nodes and pleural exudate. These organisms were cultured from the exudate and identified serologically as belonging to Lancefield's group C.