Abstract
Association between apolipoprotein B (apo B) promoter haplotypes and cholesterol concentration was studied in two groups of children with low and high concentrations of cholesterol. Strong linkage equilibrium was demonstrated between I/D in the signal peptide of apo B and (C-516T) polymorphism in the promotor of apo B gene, and the I/I + allele T haplotype was associated with a low cholesterol concentration.