A model for the drift of ions under a non-uniform, high-frequency electric field in the drift chamber of a spectrometer of ion mobility increment is developed. For the general dependence of the ion mobility on the electric field strength and the general time-dependence of the separating voltage, we suggest a procedure for calculating of the ion peak form. The shape of the peak for the ion focusing and defocusing conditions has been obtained.
BuryakovI.A.KrylovE.V.MakasA.L.NazarovE.G.PervukhinV.V. and RasulevU.K., “Separation of Ions According to Mobility in Strong AC Electric Fields”, Soviet Tech. Phys. Lett.17(12), 60 (1991).
3.
BuryakovI.A.KrylovE.V.NazarovE.G. and RasulevU.K., “A New Method of Separation of Multi-Atomic Ions by Mobility at Atmospheric Pressure Using a High-Frequency Amplitude-Asymmetric Strong Electric Field”, Int. J. Mass Spectrom. Ion Processes128, 143 (1993). doi: 10.1016/0168-1176(93)87062-W
4.
GuevremontR. and PurvesR.W., “Atmospheric Pressure Ion Focusing in a High-Field Asymmetric Waveform Ion Mobility Spectrometer”, Rev. Sci. Instrum.70, 1370 (1999). doi: 10.1063/1.1149599
5.
PurvesR.W. and GuevremontR., “Electrospray Ionization High-Field Asymmetric Waveform Ion Mobility Spectrometry-Mass Spectrometry”, Anal. Chem.71, 2346 (1999). doi: 10.1021/ac981380y
6.
ElistratovA.A. and ShibkovS.V., “An Analysis of the Nonlinear Ion Drift Spectrometry for Gas Detectors with Separating Chamber of Planar Geometry”, Tech. Phys. Lett.29(1), 81 (2003). doi: 10.1134/1.1544357
7.
ElistratovA.A. and ShibkovS.V., “A Model of Nonlinear Ion Drift Spectrometry for Gas Detectors with Separating Chamber of Cylindrical Geometry”, Tech. Phys. Lett.30(3), 183 (2004). doi: 10.1134/1.1707161
8.
ShvartsburgA.A.TangK. and SmithR.D., “Modeling the Resolution and Sensitivity of FAIMS Analyses”, J. Am. Soc. Mass Spectrom.15, 1487 (2004). doi: 10.1016/j.jasms.2004.06.018
9.
ShvartsburgA.A.TangK. and SmithR.D., “Optimization of the Design and Operation of FAIMS Analyzers”, J. Am. Soc. Mass Spectrom.16, 2 (2005). doi: 10.1016/j.jasms.2004.09.009
10.
ShvartsburgA.A.TangK. and SmithR.D., “FAIMS Operation for Realistic Gas Flow Profile and Asymmetric Waveforms Including Electronic Noise and Ripple”, J. Am. Soc. Mass Spectrom.16, 1447 (2005). doi: 10.1016/j.jasms.2005.04.003
11.
BuryakovI.A., “Coefficient of Ion Mobility Versus Electric Field Strength Dependence in Gases: Experimental Determination”Tech. Phys.47(11), 1453 (2002).
12.
ViehlandL.A.GuevremontR.PurvesR.W. and BarnettD.A., “Comparison of High-Field Ion Mobility Obtained from Drift Tubes and a FAIMS Apparatus”, Int. J. Mass Spectrom.197, 123 (2000). doi: 10.1016/S1387-3806(99)00224-9
13.
SpanglerG.E. and MillerR.A., “Application of Mobility Theory to the Interpretation of Data Generated by Linear and RF Excited Ion Mobility Spectrometers”, Int. J. Mass Spectrom.214, 95 (2002). doi: 10.1016/S1387-3806(01)00566-8
14.
KrylovE.NazarovE.G.MillerR.A.TadjikovB. and EicemanG.A., “Field Dependence of Mobilities for Gas-Phase-Protonated Monomers and Proton-Bound Dimers of Ketones by Planar Field Asymmetric Waveform Ion Mobility Spectrometer (PFAIMS)”, J. Phys. Chem. A106, 5437 (2002). doi: 10.1021/jp020009i
15.
BarnettD.A.EllsB.GuevremontR.PurvesR.W. and ViehlandL.A., “Evaluation of Carrier Gases for Use in High-Field Asymmetric Waveform Ion Mobility Spectrometry”, J. Am. Soc. Mass Spectrom.11, 1125 (2000). doi: 10.1016/S1044-0305(00)00187-2
16.
McCooeyeM.A.MesterZ.EllsB.BarnettD.A.PurvesR.W. and GuevremontR., “Quantitation of Amphetamine, Methamphetamine, and Their Methylenedioxy Derivatives in Urine by Solid-Phase Microextraction Coupled with Electrospray Ionization–High-Field Asymmetric Waveform Ion Mobility Spectrometry–Mass Spectrometry”, Anal. Chem.74, 3071 (2002). DOI 10.1021/ac011296+
17.
EllsB.BarnettD.A.PurvesR.W. and GuevremontR., “Detection of Nine Chlorinated and Brominated Haloacetic Acids at Part-per-Trillion Levels Using ESI-FAIMS-MS”, Anal. Chem.72, 4555 (2000). doi: 10.1021/ac000341v
18.
BuryakovI.A., “Express Analysis of Explosives, Chemical Warfare Agents and Drugs with Multicapillary Column Gas Chromatography and Ion Mobility Increment Spectrometry”, J. Chromatogr. B800, 75 (2004).
19.
MasonE.A. and McDanielE.W., Transport Properties of Ions in Gases.John Wiley & Sons, New York, USA, (1988).
20.
LandauL.D. and LifshitzE.M.Fluid Mechanics, Vol. 6, (Course of Theoretical Physics). Nauka: Moscow, Russia (1986).
21.
MitchellD.W., “Realistic simulation of the ion cyclotron resonance mass spectrometer using a distributed three-dimensional particle-in-cell code”, J. Am. Soc. Mass. Spectrom.10, 136 (1999). doi: 10.1016/S1044-0305(98)00130-5
22.
FedorenkoR.P., Introduction into Computational Physics.Moscow Institute of Physics and Technology Publishers, Moscow, Russia (1994).
23.
NikolaevE.N. and VedenovA.A.“The Theory of FAIMS in Coaxial Cylinders Configuration”, Proceedings of the 52nd ASMS Conference on Mass Spectrometry and Allied Topics, Nashville, TN, USA, (2004).
24.
ArnoldV.I., Geometrical Methods in the Theory of Ordinary Differential Equations.Springer-Verlag, New York, USA (1988).