The Effect of Phenyl Substitution on the Thermochemistry of Gas-Phase Ions and Their Neutral Counterparts

Abstract

The available data for the heats of formation of phenyl-substituted organics have been critically evaluated. Phenyl substitution is always thermochemically destabilizing in that Δ_fH⁰[R–C₆H₅] – Δ_fH⁰[R–H] is a positive quantity. The magnitude of the effect in neutrals depends on the substitution site, e.g. from + 79 kJ mol⁻¹ for HCOR or HCCR to + 155 kJ mol⁻¹ for RCO₂H. Multiple phenyl substitution (where possible) at the same site is generally simply additive. For the corresponding cationic species, the first phenyl substitution is stabilizing when the ionization energy of the substrate is lowered thereby and for even-electron ions resonance-stabilization energies may also come into play. Additional phenyl substitution at the same site is, however, always destabilizing. Phenyl substitutions were compared with vinyl substitution: for neutral species the effects are similar, whereas for even-electron ions, multiple vinyl substitution is only weakly stabilizing or destabilizing.