The fragmentations of alkali metal–peptide complexes of the form [M + Cat]+ have been studied by means of high and low energy tandem mass spectrometry. Small neutral losses from the precursor ion can be attributed to charge remote fragmentations along the pendant chains of certain amino acids such as arginine, lysine and methionine. The losses vary according to the structure of the amino acid side chain and in some instances provide a rapid means of verifying the absence or presence of one of these residues.
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