Abstract
The operation of the heart and of the human circulation system is described and the flow properties of blood are considered in relation to an artificial pumping and oxygenation system. The requirements of such a system are described and discussed with particular reference to their practical operation, including the requirements for a simple and reliable control system. Some ideas are presented on the future trends of such machines.
Get full access to this article
View all access options for this article.
References
1.
Dittmer
D. S.
Grebe
R. M.
Handbook of circulation
1959 (W. B. Saunders Co. , Philadelphia and London ).
2.
Casson
N.
Chapter in Rheology of disperse systems
1959 (editor
Mill
C. C.
) (Pergamon Press , London and New York ).
3.
Scott Blair
G. W.
‘An equation for the flow of blood, plasma and serum through glass capillaries’ . Nature
1959
183 , 613 .
4.
Merrill
E. W.
Wells
R. E.
jun.
‘Flow properties of biological systems’ , Appl. Mech. Rev.
1961
14 , 663 .
5.
Copley
A. L.
Chapter in Flow properties of blood , 1960 (editor
Copley
A. L.
) (Pergamon Press , London and New York ).
6.
Gibbon
J. H.
‘An oxygenator with a large surface volume ratio’ , J. Lab. Clin. Med.
1939
24 , 1192 .
7.
Gibbon
J. H.
Kraul
C. W.
‘An efficient oxygenator for blood’ , J. Lab. Clin. Med.
1941
26 , 1803.
8.
Allen
J. G.
(editor) Extracorporeal circulation
1958 (C. C. Thomas , Springfield, Illinois ).
9.
Clowes
G. H.
jun.
Physiol. Rev.
1960
40 , 826 .
10.
Hall
J. E.
James
P. A.
Lucas
B. G.
Waterston
D. J.
‘Some observations on industrial pumps for extra-corporeal circulation in man’ , Thorax
1958
13 , 34 .
11.
Shore
D. T.
‘Heat exchange in profound hypothermia’ , Proc. Instn mech. Engrs, Lond.
1963
177 .
12.
Müller
A.
‘Uber die Verwendung des Castelli-Prinzips zur Geschwindigkeitsmessung’ , Helv. Physiol. Acta
1954
12 , 300 .
13.
Melrose
D. G.
‘Pumping and oxygenating systems’ , Brit. J. Anaesthesia
1959
31 , 393 .
14.
Borst
H. G.
‘Die kunstlichen oxygenatoren’ , Thorax Chirurgie
1959
6 , 312 .