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Abstract

The application of image analysis techniques to the characterization of wear particles from failed joint replacements has been described. Wear particles were extracted from periprosthetic tissues collected during revision surgery. Chemical digestive methods were used to separate the wear particles from the biological soft material. The particles isolated were examined by optical and scanning electron microscopy. Digitized particle images were analysed on a Macintosh computer by a specially developed software and by the image analysis program ‘Prism’. The following numerical descriptors were used to characterize the particles: particle size, boundary fractal dimension and shape parameters such as form factor, roundness, convexity and aspect ratio. Elemental composition of the particles was determined by energy dispersive X-ray spectroscopy. Three selected types of wear particles were analysed and compared: titanium (Ti)-based and calcium (Ca)-based particles from a hip prosthesis and ultra-high molecular weight polyethylene (UHMWPE) particles from a knee prosthesis. The particles exhibited significantly different sizes and their shape numerical descriptors were also different. From the results obtained it appears that computer image analysis of wear particle morphology can be employed to determine the wear processes occurring in the joints. In some cases, the condition of the joint can also be assessed based on this analysis.

Keywords

wear particles joint replacements numerical descriptors boundary fractal dimension image analysis

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References

Willert

H. G.

Semlitch

Reaction of the articular capsule to plastic and metallic wear products from joint endoprostheses

Suitzer Technical Review, 1975, 2, 119–133.

Goldring

S. R.

Schiller

A. L.

Roelke

Rourke

C. M.

O'Neill

D. A.

Harris

W. H.

The synovial-like membrane at the bone-cement interface in loose total hip replacements and its proposed role in bone lysis

J. Bone Jt Surg. (Am.), 1983, 65-A, 575–584.

Agins

H. J.

Alcock

N. W.

Bansal

Salvati

E. A.

Wilson

P. D.

Pellicci

P. M.

Balloagh

Metallic wear in failed titanium-alloy total hip replacement: A histological and quantitative analysis

J. Bone Jt Surg. (Am.), 1988, 70-A, 347–356.

Maloney

W. J.

Jasty

Harris

W. H.

Galaitc

J. O.

Callaghan

J. J.

Endosteal erosion in association with stable uncemented femoral components

J. Bone Jt Surg. (Am.), 1990, 72-A, 1025–1034.

Nasser

Campbell

P. A.

Kilgus

Kossovsky

Amstutz

H. C.

Cementless total joint arthroplasty prostheses with titanium-alloy articular surfaces

Clin. Orthop., 1990, 261, 171–181.

Howie

D. W.

Tissue response in relation to type of wear particles around failed hip arthroplasties

J. Arthroplasty, 1990, 5, 337–348.

Willert

H.-G.

Bertram

Buchhorn

G. H.

Osteolysis in alloarthroplasty of the hip. The role of bone cement fragmentation

Clin. Orthop., 1990, 258, 108–121.

Willert

H.-G.

Bertram

Buchhorn

G. H.

Osteolysis in alloarthroplasty of the hip. The role of ultra-high molecular weight polyethylene wear particles

Clin. Orthop., 1990, 258, 95–107.

Collier

J. P.

Mayor

M. B.

Jensen

R. E.

Mechanisms of failure of modular prostheses

Clin. Orthop., 1992, 285, 129–139.

10.

Peters

P. J.

Jr Engh

G. A.

Dwyer

K. A.

Vinh

T. N.

Osteolysis after total knee arthroplasty without cement

J. Bone Jt Surg. (Am.), 1992, 74-A, 864–876.

11.

Huk

O. L.

Bansal

Betts

Rimnac

C. M.

Lieberman

J. R.

Huo

M. H.

Salvati

E. A.

Polyethylene and metal debris generated by non-articulating surfaces of modular acetabular components

J. Bone Jt Surg. (Am.), 1994, 76-B, 568–574.

12.

Shanbhag

A. S.

Jacobs

J. J.

Giant

T. T.

Gilbert

J. L.

Black

Galante

J. O.

Composition and morphology of wear debris in failed uncemented total hip replacement

J. Bone Jt Surg., 1994, 76-B, 60–67.

13.

Mjoberg

Theories of wear and loosening of hip prostheses

Acta Orthop. Scand., 1994, 65, 361–371.

14.

Kossovsky

Liao

Gelman

Millett

Size and mass quantification of sub-micron particulars in human synovial tissues recovered at revision

Trans. Soc. Biomater., 1991, 14, 242.

15.

Lee

J.-M.

Salvati

E. A.

Betts

DiCarlo

E. F.

Doty

S. B.

Bullough

P. G.

Size of metallic and polyethylene debris particles in failed cemented total hip replacements

J. Bone Jt Surg. (Br.), 1992, 74-B, 380–384.

16.

Margevicius

K. J.

Bauer

T. W.

McMahon

J. T.

Brown

S. A.

Merritt

Isolation and characterization of debris in membranes around total joint prostheses

J. Bone Jt Surg., 1994, 76-A, 1664–1675.

17.

Campbell

Belcher

A method for metal and particle isolation from periprosthetic tissues

Trans. Orthop. Res. Soc., 1993, 39, 494.

18.

Russ

J. C.

Computer-Assisted Microscopy, 1990 (Plenum Press, New York).

19.

Kirk

T. B.

Stachowiak

G. W.

Batchelor

A. W.

Fractal parameters and computer image analysis applied to wear particles isolated by ferrography

Wear, 1991, 145, 347–365.

20.

Kirk

T. B.

Stachowiak

G. W.

Fractal computer image analysis applied to wear particles from arthritic and asymptomatic human joints

J. Orthop. Rheumatology, 1991, 4, 13–30.

21.

Hamblin

M. G.

Stachowiak

G. W.

Comparison of boundary fractal dimensions from projected and sectioned particle images, Part I—Technique evaluation

J. Computer Assisted Microscopy, 1993, 5, 291–300.

22.

Hamblin

M. G.

Stachowiak

G. W.

Comparison of boundary fractal dimension from projected and sectioned particle images, Part II—Dimension changes

J. Computer Assisted Microscopy, 1993, 5, 301–308.

23.

Campbell

On aseptic loosening of total hip replacements: the role of UHMWPE wear particles. PhD thesis, Goteborg University, Sweden, 1995.

24.

Seifert

W. W.

Westcott

V. C.

A method for the study of wear particles in lubricating oil

Wear, 1972, 21, 27–42.

25.

Evans

C. H.

Bowen

E. R.

Bowen

Tew

W. P.

Westcott

V. C.

Synovial fluid analysis by ferrography

J. Biochem. Biophys. Methods, 1980, 2, 11–18.

26.

Mandelbrot

B. B.

The Fractal Geometry of Nature, 1982 (W. H. Freeman, New York).

27.

Stachowiak

G. W.

Hamblin

M. G.

Application of fractals to the description of shape of the particles found in tribological systems. Proceedings of the 4th International Tribology Conference, AUSTRIB 94, Frontiers in Tribology, 5–8 December 1994, Vol. I (Ed. Stachowiak

G. W.

), 1994, 181–190.

28.

Kaye

B. H.

A Random Walk through Fractal Dimensions, 1989 (VCH Verlagsgesellschaft, Weinheim, Germany).

29.

Korvin

Fractal Models in the Earth Sciences, 1992 (Elsevier).

30.

Anderson

D. P.

Wear Particle Atlas, Naval Air Engineering Centre, Technical Report NAEC-92–163, 1982.

31.

McKellop

H. A.

Campbell

Park

S.-H.

Schmaizried

T. P.

Grigoris

Amstutz

H. C.

Sarmiento

The origin of submicron polyethylene wear debris in total hip arthropasty

Clin. Orthop. Rel. Res., 1995, 311, 1–18.

32.

Campbell

Yeom

McKellop

Schmaizried

T. P.

Amstutz

H. C.

Isolation of predominately submicron sized UHMWPE wear paricles from periprosthetic tissues

J. Biomed. Mater. Res., 1995, 29, 127–131.

Application of numerical descriptors to the characterization of wear particles obtained from joint replacements

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