Use of hypnotics in patients with chronic obstructive pulmonary disease

1. Midgren B , Hansson L , Skeidsvoll H , Elmqvist D . The effects of nitrazepam and flunitrazepam on oxygen desaturation during sleep in patients with stable hypoxemic nonhypercapnic COPD . Chest 1989; 95: 765-768 .

2. Guilleminault C . Benzodiazepines, breathing, and sleep . Am J Med 1990; 88: 25S-28S .

3. Murciano D , Armengaur MH , Cramer PH et al. Acute effects of zolpidem, triazolam and flunitrazepam on arterial blood gases and control of breathing in severe COPD . Eur Respir J 1993; 6: 625-629 .

4. George CE Perspectives on the management of insomnia in patients with chronic respiratory disorders . Sleep 2000; 23: S31-S35 .