Dehydroepiandrosterone (DHEA) for serious disease,a possibility?

van Volenhoven RF , Park JL , Genovese MC et al. A double-blind, placebo-controlled, clinical trial of dehydroepiandrosterone in severe systemic lupus erythematosus . Lupus (1999) 8: 181–187 .

Bombardier C , Gladman DD , Urowitz MB . Derivation of the SLEDAI . Arthritis Rheum 1992; 35: 630–640 .

Tan EM , Cohen AS , Fries JF , et al. The 1982 revised criteria for the classification of SLE . Arthritis Rheum 1982; 25: 1271–1277 .

Reveille JD . Major Histocompatibility Complex Class II and Non-major Histocompatibility Complex Genes in the Pathogenesis of Systemic Lupus Erythematosus. In: Lahita R , (ed) Systemic Lupus Erythematosus. San Diego: Academic Press , 1999: pp 67–90.

Petri M , Lahita R , McGuire JL , et al, Results of the GL701 (DHEA) multicentre steroid sparing SLE study . Arthritis Rheum 1997; 1769: S327-S327 (Abstract).

Suzuki N , Suzuki T , Sakane T . Hormones and Lupus: defective dehydroepiandrosterone activity induces impaired interleukin-2 activity of T lymphocytes in patients with systemic Lupus erythematosus . Ann Med Interne. Paris 1996; 147: 248–252 .

Van Vollenhoven R , Engleman EG , McGuire JL . Dehydroepiandrosterone in systemic Lupus erythematosus. Results of a double-blind, placebo-controlled, randomized clinical trial . Arthritis Rheum 1995; 38: 1826–1831 .

Van Vollenhoven R , McGuire JL . Studies of dehydroepiandrosterone (DHEA) as a therapeutic agent in systemic lupus erythematosus . Ann Med Interne. Paris 147: 290–296 .

Lahita RG , Cheng CY , Monder C , Bardin CW . Experience with 19-nortestosterone in the therapy of systemic Lupus erythematosus worsened disease after treatment with 19-nortestosterone in men and lack of improvement in women . J Rheumatol 1992; 19: 547–555 .

Baulieu E-E . Dehyroepiandrosterone (DHEA): A fountain of youth? J Clin Endo Metab 1997; 81: 3147–3151 .

Spencer NFL , Poynter ME , Hennebold JD , Mu HH , Daynes RA . Does DHEAS restore immune competence in aged animals through its capacity to function as a natural modulator of peroxisone activities? In: Bellino FL , Daynes RD , Hornsby PJ , Lavren DH , Nestler JE , (eds). Dehydroepiandrosterone (DHEA) and Aging. New York: New York Academy of Sciences , 1996; pp 200–216.