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Abstract

Spontaneous hemorrhage is a rare complication of lupus. We describe a 36-year old female with lupus who suffered spontaneous, nontraumatic hemorrhage from branches of the splenic artery with massive blood loss while being treated for a lupus flare. We compare this to the two other reported cases of similar lupus-associated splenic artery hemorrhage documented in the literature, both of which had significant pre-existing hemorrhagic risk factors. Spontaneous, nontraumatic hemorrhage of the splenic artery in the absence of risk factors, and in a patient with secondary antiphospholipid syndrome, has been previously undescribed in lupus.

Keywords

antiphospholipid hemorrhage lupus splenic artery

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References

Wilson WA , Gharavi AE , Koike T et al. International consensus statement on preliminary classification criteria for definitive antiphospholipid syndrome , Arthritis Rheum 1999; 42: 1309-1311 .

Lockshin MD. Antiphospholipid antibody syndrome. In Ruddy S , Harris ED , Sledge CB et al. eds. Kelley’s Textbook of Rheumatology, 6th ed. Philadelphia: W.B. Saunders , 2001: 1146-1147.

Edworthy SM. Clinical manifestations of systemic lupus erythematosus. In Ruddy S , Harris ED , Sledge CB et al. eds. Kelley’s Textbook of Rheumatology, 6th ed. Philadelphia: W.B. Saunders , 2001: 1114-1114.

Erkan D , Cervera R , Asherton RA. Catastrophic antiphospholipid syndrome . Arthritis Rheum 2003; 48: 3320-3327 .

Santos-Ocampo AS , Mandell BF , Fessler BJ. Alveolar hemorrhage in systemic lupus erythematosus . Chest 2000; 118: 1083-1090 .

Sultan SM , Ioannou Y , Isenberg DA. A review of gastrointestinal manifestations of systemic lupus erythematosus , Rheumatology 1999; 38: 917-932 .

Karassa FB , Isenberg DA. Spontaneous rupture of the spleen: an unusual complication of systemic lupus erythematosus . Lupus 2001; 10: 876-878 .

Rosner S , Ginzler E , Diamond H. Spontaneous rupture of splenic artery and cerebrovascular accident with systemic lupus erythematosus . NY State Med J 1981; 81: 940-942 .

Johnson JF. Systemic lupus erythematosus with abdominal crisis . J Tenn Med Assoc 1986; 79: 13-14 .

10.

Duncan HV , Achara G. A rare initial manifestation of systemic lupus erythematosus - acute pancreatitis: case report and review of the literature . J Am Board Fam Pract 2003; 16: 334-338 .

Spontaneous splenic artery hemorrhage with secondary antiphospholipid syndrome in lupus: a case report

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