Systemic lupus erythematosus (SLE) can affect any part of the central nervous system (CNS) from the cerebrum to the cauda eqina, giving rise to diverse neurological mainfestations. Despite clinically apparent symptoms and signs, imaging will commonly be normal while at times the magnitude of changesdemonstratedon MRI may be out of proportionto the clinical presentation.We describethe MRI techniques used in CNS imaging and the pattern of presentation in SLE.
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