We report a case of a patient with clinical features of progressive supranuclear palsy and raised titres of anticardiolipin antibodies in blood, thrombocytopenia and livedo reticularis on skin. Magnetic resonance imaging of brain and isotope scan of brain were distinctive of vascular disorder.
Wilson WA , Gharavi AE , Koike Tet al.International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop . Arthritis Rheum1999; 42(7): 1309-1311 .
2.
Victor M , Ropper AH.Progressive supranuclear palsy. In Adams , Victor M (eds). Principles of Neurology, 7th edn.McGraw-Hill: New York , 2001, pp 1138-1140.
3.
Dubinski RM , Jankovic J.Progressive supranuclear palsy and multi-infarct state . Neurology1987; 37(4): 570-576 .
4.
Steele JC , Richardson J , Olszewski J.Progressive supranuclear palsy: a heterogenous degeneration involving the brainstem, basal ganglia and cerebellum with vertical gaze palsy and pseudobulbar palsy, nuchal dystonia, and dementia . Arch Neurol1964; 2: 473-486 .
5.
Brey RL , Hart RG , Sherman DG , Tegeler CH.Antiphospholipid antibodies and cerebral ischemia in young people . Neurology1990; 40: 1190-1196 .
6.
Tietjen GE , Day M , Norris Let al.Role of anticardiolipin antibodies in young persons with migraine and transient focal neurologic events: a prospective study . Neurology1998; 50(5): 1433-1440 .
7.
Cervera R , Asherson RA , Font Jet al.Chorea in the antiphopholipid syndrome. Clinical, radiologic, and immunologic characteristics of 50 patients from our clinics and the recent literature . Medicine (Balt)1997; 76(3): 203-212 .
8.
Coull BM , Bourdette DN , Goodnight SH Jr , Briley DP , Hart R.Multiple cerebral infarctions and dementia associated with anticardiolipin antibodies . Stroke1987; 18(6): 1107-1112 .
9.
Levine SR , Brey RL.Neurological aspects of antiphospholipid antibody syndrome . Lupus1996; 5: 347-353 .
10.
Mochizuki H , Okano M , Nagata N , Kamakura K.[A case of Sjogren’s syndrome with a high titer of anticardiolipin antibody that developed as parkinsonism.]Rinsho Shinkeigaku1997; 37(1): 57-59 . (In Japanese.)
