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Abstract

Moyamoya disease is an uncommon clinical entity, characterized by bilateral occlusion of the internal carotid artery and the development of collateral arteries. An 18-year-old Saudi male with systemic lupus erythematosus (SLE) presented with mild right hemiparesis, followed by recurrent ischemic stroke. Cerebral angiography showed bilateral internal carotid artery stenosis associated with the development of collateral circulation (moyamoya vessels). There was no evidence of active SLE or other risk factors for cerebral occlusion, such as antiphospholipid antibody syndrome. Medical and surgical interventions did not influence the poor outcome of the recurrent ischemic insults.

Keywords

moyamoya syndrome systemic lupus erythematosus ischemic stroke angiography papular mucinosis

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Futrell N , Millikan C . Frequency, etiology, and prevention of stroke in patients with systemic lupus erythematosus . Stroke 1989; 20: 583–591 .

Mitsias P , Levine SR . Large cerebral vessel occlusive disease in SLE . Neurology 1994; 44: 385–393 .

Toubi E , Khamashta M , Panarra A , Hughes G . Association of antiphospholipid antibodies with central nervous system disease in SLE . Am J Med 1995; 99: 397–401 .

Garg BP , Bruno A , and Biller J . Moyamoya disease and cerebral ischemia. In: Batjer HH (ed). Cerebrovascular Disease. Lippincott-Raven: Philadelphia , 1997, pp 489–499.

Suzuki J , Takaku A . Cerebrovascular moyamoya disease showing abnormal netlike vessels in base of brain . Arch Neurol 1969; 20: 288–299 .

Kitamura K , Fukui M , Oka K . Moyamoya disease. In: Toole JF. Vascular Diseases. In: Vinken PJ , Bruyn GW , Klawans HL , (ed). Handbook of Clinical Neurology, vol 11. Elsevier: New York , 1989, pp 293–306.

Fukui M . Diagnostic guidelines for spontaneous occlusion of the Circle of Willis (‘Moyamoya’ disease) . In: Fukui M , (ed). Annual Report (1995) of the Research Committee on Spontaneous Occlusion of the Circle of Willis (‘Moyamoya’ Disease) of the Ministry of Health and Welfare, Japan (in Japanese), 1996, pp 143–166 .

Fujiwara S , Miyazono M , Tsuda H , Fukui M . Intraventricular hemorrhage and cerebral ischemic attacks in the presence of lupus anticoagulant mimicking moyamoya disease . J Neurosurg Sci 1993; 37: 161–164 .

Matsuki Y , Kawakami M , Ishizuka T et al. SLE and Sjögren's syndrome associated with unilateral moyamoya vessels in cerebral arteries . Scand J Rheumatol 1997; 26: 392–394 .

10.

Wanifuchi H , Kagawa M , Takeshita M et al. Auto-immune antibody in moyamoya disease (in Japanese) . Neurosurgery 1986; 14: 31–35 .

11.

Provost TT , Moses H , Morris EL et al. Cerebral vasculopathy associated with collateralization resembling moyamoya phenomenon and with anti-Ro/SSA and anti-La/SSB antibodies . Arthritis Rheum 1991; 34: 1052–1055 .

12.

Alexander EL , Craft C , Provost TT et al. Necrotizing arteritis and spinal sub-arachnoid hemorrhage in Sjögren's syndrome . Ann Neurol 1982; 11: 632–635 .

13.

Yoshida Y , Yoshimoto T , Shirane R , Sakurai Y . Clinical course, surgical management, and long-term of moyamoya patients with rebleeding after an episode of intracerebral hemorrhage: an extensive follow-up study . Stroke 1999; 30: 2272–2276 .

14.

Yonekawa Y . Summary report of the research committee on spontaneous occlusion of the circle of willis (moyamoya disease) (1988–1992) . In: Yonekawa Y , (ed). 1992 Annual Report of the Recsearch Committee on Spontaneous Occlusion of the Circle of Willis (Moyamoya Disease). Japanese Ministry of Health and Welfare: Tokyo, 1992, pp 1–11 .

Systemic lupus erythematosus associated with moyamoya syndrome

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