Befort, K, Kieffer BL. Structure–activity relationships in the S-opioid receptor. Pain Rev1997; 4: 100–121.
2.
Capecchi MR. Altering the genome by homologous recombination. Science1989; 244: 288–1292.
3.
Schuller AGP, King MA, Zhang J et al. Retention of heroin and morphine-6-glucuronide analgesia in MOR-1 exonI knockout mice insensitive to morphine: evidence for a novel MOR-1-related receptor. Nat Neurosci1999; 2: 151–156.
4.
Abbott RM, Palmour RM. Morpine-6-glucuronide: analgesic effects and receptor binding profile in rats. Life Sci1998; 43: 1685–1695.
5.
Lehmann KA, Zech D. Morphine-6-glucuronide, a pharmacologically active morphine metabolite: a review of the literature. Eur J Pain1993; 14: 28–35.
6.
Schuller AGP, King M, Zhang J et al. Herion and M6G analgesia are retained in mu opioid receptor deficient mice. Soc Neurosci Abs1997; 23: 584.
7.
Rossi G, Leventhal L, Pan Y-X et al. Antisense mapping of MOR-I in rats: distinguishing between morphine and morphine-6-glucuronide antinociception. J Pharmacol Exp Ther1997; 281: 109–114.