Radiobiological experiments with accelerated heavy charged particles have been stimulated mainly by the medical application of heavy ion beams in radiotherapy, radiography, microsurgery and diagnostic application. Some of these new medical applications are still in the phase of pilot studies or animaJ experiments, but some others, like the treatment of the ocular melanomas, have become a routine procedure at Berkeley and Harvard.
Get full access to this article
View all access options for this article.
References
1.
SkarsgardL. D.(Ed.), Pion and Heavy Ion Radiotherapy, Preclinical and Clinical Studies, Oxford, New York (1982).
2.
PirucelloM. and TobiasC. A.(Ed.), Biological and Medical Research with Accelerated Heavy Ions at the Bevalac, University of California, Berkeley (1980).
3.
KellererA. M., Microdosimetric concepts relevant to hze-particles.Proceedings of the European Symposium on Lifesciences research in space, p. 271. European Space Agency, Cologne (1977).
4.
KieferJ., RaseS., SchöpferF., SchneiderE., WeberK., KraftG., Heavy ion action on yeast cells. Adv. in Space Research3(8), pp. 115–125 (1983), G, Kraft, W. Kraft-Weyrather, H, Meister, H. G. Miltenburger, R. Roots and H. Wulf, The influence of radiation quality on the biological effectiveness of heavy charged particles. Proceedings of the 8th Symposium on Microdosimetry, p. 743. Commission of the European Communities, Luxembourg (1982).
5.
KatzR., SharmaS. C. and HomayoonfarM., Detection of energetic heavy ions Nuclear Instruments and Methods100, 13 (1973).
6.
HallE. J., Radiobiology for the Radiologist, p. 104ff. Harper and Row, New York (1978).
7.
SchäferM., FaciusR., BaltschukatK and BückerH., gsi-Report1980. GSI82–2, p. 158.
8.
KraftG. et al., Irradiation chamber and sample changer for biological samples. Nuclear Instruments and Methods168, 175 (1980).
9.
MüllerW., MiltenburgerH. G. and KraftG., Chromosome aberrations in Chinese hamster cell cultures induced by heavy ion irradiation, B4–26Proc. 7th int. Congr. of Rad. Res.Amster dam, July1984.