The treatment of transplant patients is becoming an ever-increasing part of modern-day orthodontic practice. This report details the successful orthodontic management of a paediatric renal transplant patient with significant drug-induced gingival overgrowth. The problems that such patients present with are discussed before considering the specific orthodontic techniques employed. Recommendations are made for practitioners managing such cases.
WrightG, WelburyRR, HoseyMTCyclosporin-induced gingival overgrowth in children. Int J Paediatr Dent2005; 15: 403–11.
2.
ChabriaD, WeintraubRG, KilpatrickNMMechanisms and management of gingival overgrowth in paediatric transplant recipients: a review. Int J Paediatr Dent2003; 13: 220–29.
3.
ProctorR, KumarN, SteinA, MolesD, PorterSOral and dental aspects of chronic renal failure. J Dent Res2005; 84: 199–208.
4.
SeymourRA, JacobsDJCyclosporin and the gingival tissues. J Clin Periodontol1992; 19: 1–11.
5.
ThomasonJM, SeymourRA, RiceNThe prevalence and severity of cyclosporin and nifedipine-induced gingival overgrowth. J Clin Periodontol1993; 20: 37–40.
ThomasonJM, SeymourRA, EllisJSRisk factors for gingival overgrowth in patients medicated with ciclosporin in the absence of calcium channel blockers. J Clin Periodontol2005; 32: 273–79.
8.
SoamesJV, SouthamJC. Oral Pathology, 3rd edn. New York: Oxford University Press, 1998, 3–17.
9.
KantarciA, CebeciI, TuncerO, CarinM, FiratliEClinical effects of periodontal therapy on the severity of cyclosporin A-induced gingival hyperplasia. J Periodontol1999; 70: 587–593
10.
SeymourRA, SmithDGThe effect of a plaque control programme on the incidence and severity of cyclosporin-induced gingival changes. J Clin Periodontol1991; 18: 107–10.
11.
DaleyTD, WysockiGP, MamandrasAHOrthodontic therapy in the patient treated with cyclosporine. Am J Orthod Dentofacial Orthop1991; 100: 537–41.
12.
WebsterAC, WoodroffeRC, TaylorRS, ChapmanJR, CraigJCTacrolimus versus ciclosporin as primary immunosuppression for kidney transplant recipients: meta-analysis and meta-regression of randomised trial data. BMJ2005; 331: 810.
