Christopher Wren's figure of the brain ‘viewed from below’ in Thomas Willis's Cerebri anatome (1664) set a precedent, not only for subsequent images of the brain, but for scientific illustration. The image is the visual proof of a Baconian experiment conducted by the Oxford dissection team, in which dye was pumped into the carotid arteries of animal and human specimens in order to imitate the natural flow of blood, thereby applying William Harvey's theory of circulation to the brain. Usually described as engravings, Wren's images are in fact etchings (produced by the acid process), significant because etching for book illustration was then in its infancy in England. In addition to considering Wren as an experimental etcher, this article frames our understanding of Wren's contributions to Willis's project in terms of his virtuosic talents as amateur draughtsman, natural historian, anatomist, and his use of optical and draughting instruments.
AlpersSvetlana. 1983. The Art of Describing: Dutch Art in the Seventeenth Century. Chicago: University of Chicago Press.
2.
ArnoldKen. 2006. Cabinets for the Curious: Looking back at Early English Museums. Aldershot: Ashgate.
3.
AshmoleElias. 1672. Institution, Laws and Ceremonies of the Most Noble Order of the Garter. London: J. Macock for Nathanael Brooke.
4.
BaconFrancis. 1620. Instauratio Magna [The Great Instauration], with Novum Organum [The New Organon or True Directions concerning the Interpretation of Nature]. London: John Bill.
5.
BaconFrancis. 1627. Sylva sylvarum: or A naturall historie in ten centuries [with New Atlantis]. London: J. H. for William Lee.
6.
Barcia GoyanesJuanJ. 1995. Notes on the historical vocabulary of neuroanatomy.History of Psychiatry6: 471–82
7.
BaxandallMichael. 1985. Patterns of Intention: on the Historical Explanation of Pictures. New Haven and London: Yale University Press.
8.
BennettJames. 1982. The Mathematical Science of Christopher Wren. Cambridge: Cambridge University Press.
9.
BennettJames, JohnstonSA, SimcockAV. 2000. Solomon's House in Oxford: New Finds from the First Museum. Oxford: Museum of the History of Science.
10.
BerminghamAnn. 2000. Learning to Draw: Studies in the Cultural History of a Polite and Useful Art. New Haven and London: Yale University Press.
11.
BidlooGottfried. 1685. Anatomia humani corporis, centum & quinque tabulis, per artificiosiss. G. de Lairesse ad vivum delineates …Amsterdam: widow of Joannes van Someren.
12.
BosseAbraham. 1645. De la manière de graver à l'eaux-forte et au burin. Paris: Charles-Antoine Jombert.
13.
BoyleRobert. 1660. New Experiments Physico-Mechanical, Touching the Spring of the Air. Oxford: H. Hall for T. Robinson.
14.
BoyleRobert. 1663. Some considerations touching the usefulnesse of experimental naturall philosophy …Oxford: H. Hall for R. Davis.
15.
BynumWilliamF. 1973. The anatomical method, natural theology and the functions of the brain.Isis64: 445–68
CavalcantiDanielD, FeindelWilliam, GoodrichJamesT, DagiTForcht, PrestigiacomoCharlesJ, PreulMarkC. 2009. Toward a realistic perspective of the brain.Neurosurgery Focus27(3): http://www.medscape.com/viewarticle/714156_4(27/04/2011).
18.
ClarkKenneth. 1966. Rembrandt and the Italian Renaissance. London: John Murray.
19.
ColesAlasdair. 3 October 1986. Communication to the Wellcome Library concerning the retro-diagnosis of a pathological specimen of an intestine, the drawing of which is attributed to Wren.
20.
DastonLorraine, LunbeckElizabeth, eds. 2011. Histories of Scientific Observation. Chicago: University of Chicago Press.
21.
DastonLorraine, GalisonPeter. 2007. Objectivity. New York: Zone Books.
22.
DaviesCSL. 2008. The Youth and Life of Sir Christopher Wren.The English Historical Review123: 300–27.
23.
DearPeter. 2001. Revolutionizing the Sciences: European Knowledge and its Ambitions, 1500–1700. Basingstoke, Hants: Palgrave.
24.
De BeerE, ed. 1955. Diary of John Evelyn, 6 vols. Oxford: Oxford University Press.
25.
EvelynJohn (commissioner). c.1646. Anatomical tables. Arteries, veins, and nerves preserved and inlaid in wood, assembled in Padua.Hunterian Collection, University of Glasgow.
26.
EvelynJohn. 1662. Sculptura, or, The history, and art of chalcography and engraving in copper …London: J. C. for G. Beedle and T. Collins.
27.
EvelynJohn. 1955. The Diary of John Evelyn. Ed. , de BeerE S. Oxford: Clarendon Press, 6 vols.
28.
FaithorneWilliamSr.. 1662. The art of graveing and etching, wherein is exprest the true way of graveing in copper. London: William Faithorne.
29.
FallopioGabriel. 1561. Observationes anatomicae. Padua: Marc Antonio Ulmo.
30.
FeindelWilliam. 1962. Thomas Willis (1621–1675) — The Founder of Neurology.The Canadian Medical Association Journal87: 289–96.
31.
FeindelWilliam, ed. 1965. Thomas Willis's Anatomy of the Brain and Nerves (Tercentenary edition). Montreal: McGill University Press.
32.
FeindelWilliam. 1996. Domus Willisi: a neuro-architectural tour.Journal of the History of Neuroscience5: 268–70.
33.
FrankRobertG. 1980. Harvey and the Oxford Physiologists: A Study of Scientific Ideas. Los Angeles: University of California Press.
34.
GerbinoAnthony, JohnstonStephen. 2009. Compass and Rule: Architecture as Mathematical Practice in England, 1500–1750. Exhibition at Oxford and New Haven, 16 June–6 September.
35.
GibsonWilliam Carleton. 1970. The Bio-Medical Pursuits of Christopher Wren.Medical History14: 331–41.
36.
GriffithsAntony. 1996. Prints and Printmaking: An introduction to the history and techniques. London: British Museum.
37.
GriffithsAntony. 2004, 2008. Faithorne, William (c.1620–1691).Oxford Dictionary of National Biography. , MatthewH C G, HarrisonBrian, ed. Oxford: Oxford University Press. Online edition.
38.
GrindleNick. 2005. ‘No other sign or note than the very order’: Francis Willughby, John Ray and the importance of collecting pictures.Journal of the History of Collections17: 15–22.
39.
HarrisonPeter, NumbersR L, ShankM H, eds. 2011. Wrestling with Nature: From Omens to Science. Chicago: University of Chicago Press.
40.
HarveyWilliam. 1628. Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus [An Anatomical Exercise on the Motion of the Heart and Blood in Living Beings]. Frakfurt: Guilielmi Fitzeri.
41.
HarveyWilliam. 1649. Exercitatio anatomica de circulatione sanguinis [An Anatomical Exercise on the Circulation of the Blood]. Cambridge: Roger Daniels.
42.
HodnettEdward. 1988. Five Centuries of English Book Illustration. Aldershot, Hants: Scholar Press.
43.
Edward HodnettEdward. 1978. Francis Barlow: First Master of English Book Illustration. Los Angeles: University of California Press.
44.
HookeRobert. 1665. Micrographia: or some Physiological Descriptions of Minute Bodies made by Magnifying Glasses with Observations and Inquiries thereupon. London: John Martyn and James Allestry.
45.
HookeRobert. 1716. Injection of Medicated Liquors and other things into the Veins of animals … about the End of Year 1656.Philosophical Transactions3: 291.
46.
JardineLisa. 2004. Dr Wilkins's Boy Wonders.Notes and Records of the Royal Society58: 107–29.
47.
JardineLisa. 2002. On a Grander Scale: the Outstanding Career of Christopher Wren. London: Harper Collins.
48.
KempMartin. 1990. The Science of Art: Optical Themes in Western Art from Brunelleschi to Seurat. New Haven and London: Yale University Press.
49.
Kemp, Martin, ed. and Cecil Grayson, trans. 1991. On Painting [Alberti's De pictura, 1435–6]. New York: Harmondsworth.
50.
KempMartin. 1996. The Temple of the Body and the Temple of the Cosmos: Vision and Visualization in the Vesalian and Copernican Revolutions.InPicturing Knowledge: Historical and Philosophical Problems concerning the use of art in science, ed. , BaigrieBrian S. Toronto: University of Toronto Press.
51.
KempMartin, FlisNathan. 2008. Mapping the Cerebral Globe: A detailed sketch by architect Christopher Wren reveals his surprising contribution to neuroscience.Nature455(7219): 174.
52.
KnoeffRina. 2004. The reins of the soul: the centrality of the intercostal nerves to the neurology of Thomas Willis and to Samuel Parker's theology.Journal of the History of Medicine and Allied Sciences.59(3): 413–40.
53.
KusukawaSachiko. 2011. Picturing Knowledge in the early Royal Society: the examples of Richard Waller and Henry Hunt.Notes and Records of the Royal Society65: 273–94.
54.
KusukawaSachiko. 2000. The Historia Piscium (1686).Notes and Records of the Royal Society of London54: 179–97.
55.
LakkeJohannesPWF. 1998. Autopsy Practices for Brain Dissections and Rembrandt's Anatomy of Dr Deyman.Journal of the History of the Neurosciences7: 101–7.
ListerMartin. 1685–92. Historiae conchyliorum. London: Author's private press.
58.
LowerRichard. 1932. The Transfusion of Blood from one animal to another (excerpt from De Corde, 1669).InEarly Science in Oxford. Ed. , GunterR T. Oxford: Oxford University Press, vol. IX, chapter IV.
59.
MacGregorArthur. 2007. Curiosity and Enlightenment: Collectors and Collections from the Sixteenth to the Nineteenth Centuries. New Haven and London: Yale University Press.
60.
MartensenRobertL. 2004. The Brain Takes Shape: An Early History. Oxford: Oxford University Press.
61.
MolnárZoltán. 2004. Thomas Willis (1621–75), the founder of clinical neuroscience.Nature Reviews Neuroscience5: 329–335.
62.
NeherAllister. 2009. Christopher Wren, Thomas Willis, and the depiction of the brain and nerves.Journal of the Medical Humanities30: 191–200.
63.
NeriJanice. 2008. Between Observation and Image: Representations of Insects in Robert Hooke's Micrographia.The Art of Natural History: Illustrated Treatises and Botanical Paintings, 1400–1850. Ed. , O'MalleyTherese, MeyersAmy R W. Washington: National Gallery of Art.
64.
OgilbyJohn. 1675. Britannia … or, An illustration of the Kingdom of England and dominion of Wales. London: J. Ogilby.
65.
OldenburgHenry, ed. An Account of the Rise and Attempts of a Way to convey Liquors immediately into the Mass of Blood.Philosophical Transactions1665, 7: 128.
66.
OldenburgHenry, ed. 1669. The Description of an Instrument invented divers years ago by Dr Christopher Wren …Philosophical Transactions4: 893.
67.
PeachamHenry. 1606. Art of Drawing with a Pen. London: Richard Braddock for William Jones.
68.
PenningtonRichard. 1982. A Descriptive Catalogue of the Etched Work of Wenceslaus Hollar, 1607–1677. Cambridge: Cambridge University Press.
69.
PlotRobert. 1677. The Natural History of Oxford-shire, being an Essay towards the Natural History of England. Oxford: University Press (Sheldonian).
70.
De RijckeSarah. 2010. Regarding the Brain: Practices of Objectivity in Cerebral Imaging, Seventeenth Century — Present. PhD thesis, University of Groningen.
71.
RoosAnna Marie. 2012. The Art of Science: a ‘Rediscovery’ of the Lister Copperplates.Notes and Records of the Royal Society, 66(1), 19–40.
72.
RuyschFrederik. 1744. Opera omnia anatomico-medico-chirirgica. Amsterdam: Jansson Waesberg.
73.
SchafferSimon. 2002. The Devices of Iconoclasm.In, LatourBruno, WeibelPeter, eds. Iconoclash. Cambridge, MA: MIT Press.
74.
ShapinSteven. 1994. A Social History of Truth: Civility and Science in Seventeenth-Century England. Chicago: University of Chicago Press.
75.
ShapinSteven. 2010. Never Pure: Historical Studies of Science as if It Was Produced by People with Bodies, Situated in Time, Space, Culture, and Society, and Struggling for Credibility and Authority. Baltimore: The Johns Hopkins University Press.
76.
ShapinSteven, SchafferSimon. 1985. Leviathan and the Air-Pump: Hobbes, Boyle, and the Experimental Life. Princeton: Princeton University Press.
77.
ShapiroBarbaraJ. A Culture of Fact: England, 1550–1720. Ithaca, NY: Cornell University Press.
78.
SloanKim. 2000. ‘A Noble Art’: Amateur Artists and Drawing Masters, c.1600–1800. London: British Museum Press.
79.
SloanKim. 1997. A New World: England's first view of America. London: British Museum.
80.
SpratThomas. 1667. The History of the Royal-Society of London, For the Improving of Natural Knowledge. London: John Martyn and James Allestry.
81.
Stensen [Steno]Niels, 1669, 1965. Lecture on the anatomy of the Brain. Copenhagen: Nyt Nordisk Forlag and Arnold Busck.
82.
StijnmanAd. 1999. On feathers, candles and wet rags: the etching technique used by Van Dyck and his contemporaries.In, DepauwCarl, LuijtenGer, eds. Anthony van Dyck as a Printmaker. Antwerp.
83.
SullivanDorothyM. 1967. Willis’ Cerebri anatome — An Original Drawing.Journal of the History of Medicine and Allied Sciences22: 182–4.
84.
SwanClaudia. 2005. Art, Science, and Witchcraft in Early Modern Holland: Jacques de Gheyn II (1565–1629). Cambridge: Cambridge University Press.
85.
TaylorEGR. 1937. Robert Hooke and the Cartographical Projects of the Late Seventeenth Century (1666–1696).The Geographical Journal90: 529–40.
86.
ThomasBen. 2010. Noble or Commercial? The Early History of the Mezzotint in Britain.InPrinted Images in Early Modern Britain, ed. , HunterMichael. Farnham, Surrey: 279–96.
87.
ThorntonJL. 1966. Medical Books, Libraries and Collectors: A Study of Bibliography and the Book Trade in Relation to the Medical Sciences. London: Library Association.
88.
TinniswoodAdrian. 2001. His Invention so Fertile: A Life of Christopher Wren. London: Pimlico.
89.
ValesioFrancesco (1560–1648). c.1627. Engraving showing the base of the human brain after Odoardo Fialetti (1573–c.1638).In Casserio, Giulio Cesare. 1627. Tabulae anatomicae LXXVIII. Venice: Evangelista Deuchino.Varolio, Constanzo. 1573. De nervis opticis. Padua: Metti.
90.
VeslingJohann. 1653. The anatomy of the body of man. Trans. Nicholas Culpeper. London: Peter Cole.
91.
WepferJohann Jacob. 1658, 1724. Historiae apoplecticorum. Amsterdam: J. Waesberg.
92.
WebsterCharles. 1975, 2002. The Great Instauration: Science, Medicine and Reform, 1626–1660. Oxford: Peter Lang.
93.
WhitakerKatie. 1996. The Culture of Curiosity.InCultures of Natural History, ed. , JardineN, SecordJ A, SparyE C. Cambridge: Cambridge University Press.
94.
WillisThomas. 1664. Cerebri anatome: cui accessit nervorum descriptio et usus. London: John Martyn and James Allestry.
95.
WillisThomas. 1666. Cerebri anatome [edition with 1665 engraved frontispiece depicting a dissection]. Amsterdam: Gerbrandt Schagen.
96.
WillisThomas. 1672. De anima brutorum. Oxford: University of Oxford (Fell) Press.
97.
WillisThomas. 1678. Pharmaceuticae rationalis. London: T. Dring, C. Harper, and J. Leigh.
98.
WillisThomas. 1681. Five Treatises. Trans. Samuel Pordage. London.
99.
WrenChristopher. c.1642–3. A prospect of the parish church at Knoyle and a view in perspective of a dining-room in his father's house there.Drawing. British Library, MS Add. 25071, fol. 87v.
100.
WrenChristopher (attributed). c.1656–8. Two views of the small intestine, with ulcers caused by typhoid fever. Watercolour on paper, with inscription, ‘Thomas Willis’ and ‘Chr. Wren’. 14·8×20·2 cm. London, Wellcome Library, no. 570945i.
101.
WrenChristopher. 1740. Communication to John Ward, 11 August.British Library, MS Add. 6209, fol. 209.
102.
WrenChristopher. 1750. Parentalia: Or, Memoirs of the Family of the Wrens; viz. of Matthew Bishop of Ely, Christopher Dean of Windsor, etc. but Chiefly of Sir Christopher Wren, Late Surveyor-General of the Royal Buildings, President of the Royal Society, etc., etc. London: T. Osborn and R. Dodsley.
