Abstract
The immune system distinguishes self from nonself permitting protection from invading microorganisms and cancer, but also causing rejection of foreign cells as in allogeneic organ transplantation. However, in sexual reproduction, the man's sperm are not rejected by the woman's immune system. This is based on the presence of a mild immunosuppressant in the seminal fluid, making possible the “two-in-one-flesh” intimacy that results in procreation. The biological consequences of natural sexual intercourse are completely distinct from the unnatural act of anal intercourse, as occurs in homosexual unions. The capacity of spermatozoa to penetrate into the nuclei of cells, coupled with the immunosuppressant in seminal fluid, greatly increases the risk of development of anal cancer. Science, which is immune to political or fashionable trends, thus bears witness to the unique nature of the conjugal bond between a man and a woman.
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