Abstract
1. A condition of reduced glomerular filtration and increased tubular reabsorption was produced experimentally in toads by the process of acute dehydration.
2. In such a condition there was an interesting change, hitherto unrecorded, in acid phosphatase and plasmalogen content of the kidney. There was a fall in plasmalogen and a rise in acid phosphatase in kidney glomeruli during dehydration, and opposite results were observed in the tubules.
3. It may be concluded that plasmalogen is related to the functional activity of the kidney; in the case of acid phosphatase, a non-functional accumulation has been observed.
4. There was also a rise in succinic acid dehydrogenase and esterase in the functioning kidney tubules during dehydration.