Endovaginal Sonographic Associated Features of a T-Shaped Uterus Due to In Utero Exposure to Diethyistilbestrol (DES)

Abstract

In utero exposure to diethylstilbestrol (DES), a synthetic estrogen, affects structures arising in the mullerian duct system of female fetuses. Transabdominal sonography has been found to be a nonionizing, noninvasive alternative to hysterosalpingography in diagnosing these congenital abnormalities. Endovaginal sonography has shown enhanced resolution of the female pelvic organs. The endovaginal features of a T-shaped uterus due to in utero DES exposure are presented in a woman with infertility.

Keywords

Endovaginal ultrasound diethylstilbestrol T-shaped uterus

References

1. Kaufman RH , Binder GL , Gray PM , et al: Upper genital tract changes associated with exposure in utero to diethylstilbestrol. Am J Obstet Gynecol 1977;128:51-59.

2. Kaufman RH , Adam E , Binder GL , et al: Upper genital tract changes and pregnancy outcome in offspring exposed in utero to diethylstilbestrol. Am I Obstet Gynecol 1980;137:299-308.

3. Kaufman RH , Adam E , Noller K , et al: Upper genital changes and infertility in diethylstilbestrol exposed women. Am I Obstet Gynecol 1986;154:1312-1312.

4. Rennel CL : T-shaped uterus in diethylstilbestrol (DES) exposure. AJR 179;132:979-980.

5. Szoke B , Kiss D : The use of ultrasonic echotechnique in the diagnosis of developmental anomalies of the uterus. Ann Chir Gynaecol 1977;66:59-61.

6. Valdes C , Malini S . Malinak R : Ultrasound evaluation of female genital tract anomalies: A review of 64 cases. Am J Obstet Gynecol 1984;149:285-292.

7. Randolph JR , Ying YK , Maier DB , et al: Comparison of real-time ultrasonography, hysterosalpingography and laparoscopy, hysteroscopy in the evaluation of uterine abnormalities and tubal patency. Fertil Steril 1986;46:828-832.

8. Fedels L , Dorta M , Vercellini P : Ultrasound in the diagnosis of subclasses of unicornuate uterus. Obstet Gynecol 1988;71:274-277.

9. Callen P . DeMartini WJ , Filly RA : The central uterine cavity echo: A useful anatomic sign in the ultrasonographic evaluation of the female pelvis. Radiology 1979;131:187-190.

10.

10. Viscomi GN , Gonzalez R , Taylor KJW , et al: Ultrasound detection of uterine abnormalities after diethylstilbestrol (DES) exposure. Radiology 1980;136:733-735.

11.

11. Mendelson EB , Bohm Velez M , Joseph N , et al: Endometrial abnormalities: Evaluation with transvaginal sonography. AIR 1988;150:139-142.