SDMS CME Credit – Prenatal Diagnosis of Bilateral Meromelia Coexisting With Duodenal Atresia: Case Report of a Rare Anomalous Combination With Three-Dimensional Sonography

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Article: Prenatal Diagnosis of Bilateral Meromelia Coexisting With Duodenal Atresia: Case Report of a Rare Anomalous Combination With Three-Dimensional Sonography

Authors: Ameen Muftiat Omolola, MBBS, Awowole Ibraheem Olayemi, FWACS, MRCOG, Abdur-Rahim Zainab Foyeke, FWACS, and Muhammad-Olodo Abdulmujeeb Opeyemi, MBBS

Category: OB/GYN [OB]

Credit: 0.50 SDMS CME Credit

Objectives: After studying the article, you should be able to:

• Discuss the causes of congenital upper limb abnormality (CULA).

• Describe the sonographic measurements obtained when fetal limb abnormalities are suspected.

• Recognize the sonographic appearance of meromelia.

1. Which of the following is characterized by incomplete development of at least one limb, resulting in partial absence of the affected limb?

2. B. Thrombocytopenia-absent-radius syndrome

3. C. Meromelia

4. D. Poland syndrome

When do the upper limbs begin to develop in utero?

A. During the first week

B. During the second week

C. During the fourth week

D. During the second trimester

Which is a differential diagnosis for duodenal atresia (DA)?

A. The “single bubble” sign

B. Anterior duplication cysts

C. Jejunal atresia

D. Aphalangia

What is the reported incidence of Meromelia per 100,000 births?

A. 1.4

B. 2

C. 3.8

D. 10

Approximately what percentage of newborns with CULA will survive the neonatal period?

A. 10%

B. 20%

C. 45%

D. 60%