Abstract
Article: Molecular Ultrasound Imaging for the Detection of Neural Inflammation: A Longitudinal Dosing Pilot Study
Authors: Kevin R. Volz, PhD, RVT, Kevin D. Evans, PhD, RT(R) (M) (BD), RDMS, RVS, Christopher D. Kanner, BS, John A. Buford, PhD, PT, Miriam Freimer, MD, Carolyn M. Sommerich, PhD, CPE, and D. Michele Basso, EdD, PT
Category: Other [OT]
Credit: 0.75 SDMS CME Credit
Objectives: After studying the article entitled “Molecular Ultrasound Imaging for the Detection of Neural Inflammation: A Longitudinal Dosing Pilot Study,” you will be able to
Describe the preclinical methods of the targeted contrast-enhanced ultrasound (TCEUS) study that was conducted.
Discuss the ways to biotinylate a contrast media bubble.
Identify the side effects of bursting microbubbles with biological tissue.
For which of the following selectins was the inflammatory biomarker tagged for investigation? P L E C
The acute stage of spinal cord injury that was imaged with TCEUS was at which time point? 0 days 7 days 32 days 42 days
Two doses of targeted contrast were given at both time points of the study, but what dose was paired with 30 μL of targeted contrast? 25 μL 50 μL 75 μL 100 μL
Bolus injections of targeted contrast were made at which of the following venous sites? Forearm Jugular Tail Scalp
The subjects underwent a laminectomy at what level of the spinal cord? T5 T7 T10 T12
Sonophoresis has been reported at what frequency levels? 10.0 MHz 8.0 MHz 4.0 MHz 2.0 MHz
Which of the following microbubble binding substances has possibly qualified for human use? Streptavidin NeutrAvidin Biotin Streptococcus
Footnotes