Fetal cerebellar anomalies are rarely isolated or asymmetric. Cerebellar hypoplasia is frequently diagnosed by second trimester prenatal sonology. The prognosis for cerebellar hypoplasia is dismal when associated with a trisomy, spina bifida, or other anomalies such as Arnold-Chiari malformation. Presented is a case of unilateral cerebellar hypoplasia with apparently normal neurologic outcome. The fetal brain anatomy appeared normal at 24 weeks gestation. Unilateral cerebellar hypoplasia was diagnosed at 32 weeks demonstrating destruction of a normally formed fetal structure. The cause was unknown.
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